Found 246 clinical trials
Connexin Genotypes in Cystic Fibrosis
Methods:Patients homozygous for delta F508 get recruited from the CF centres of Bonn, Frankfurt and Amsterdam. Sequence analysis is performed for connexin 43 and 37. Clinical disease is assessed longitudinally over 3 years by pulmonary function tests (FEV1 (forced expiratory volume in one second), FVC (=(forced vital capacity), FEF75 % …
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- 16 Feb, 2024
- 3 locations
Hyperpolarized Imaging for New Treatments
The introduction of triple combination CFTR modulator therapy for patients with Cystic Fibrosis (CF) with at least one copy of the deltaF508 mutation is expected to provide major health benefits, but will also require novel outcome measures that can detect CF lung disease at an early stage, capture the efficacy …
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- 16 Feb, 2024
- 4 locations
Intimacy of Women With Cystic Fibrosis
The intimate life of patients with cystic fibrosis has not been the subject of specific research, it is even left behind in favor of respiratory, digestive or endocrinological dysfunctions endangering these patients.
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- 16 Feb, 2024
- 1 location
A Prospective Multi-centre Single-blinded Study of UroCAD for Urothelial Carcinoma Diagnosis and Follow-up
Urothelial carcinoma (UC) is common malignancy and is considered to be one of the most expensive cancers. The traditional diagnostic methods of UC present with some shortcomings. For example, the specificity of CTU remains low while cystoscopy is invasive and expensive. Therefore, a noninvasive diagnostic method with high accuracy is …
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- 16 Feb, 2024
- 1 location
Impacts of the Covid-19 Epidemic and Associated Lockdown Measures on the Management Health and Behaviors of Cystic Fibrosis Patients During the 2020 Epidemic
Impacts of the Covid-19 epidemic and associated lockdown measures on the management, health and behaviors of cystic fibrosis patients during the 2020 epidemic
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- 16 Feb, 2024
- 3 locations
Impact of Sinus Surgery on Individuals With Cystic Fibrosis
This study will be a prospective, observational study of patients who undergo endoscopic sinus surgery for cystic fibrosis-related chronic rhinosinusitis (CRS). Individuals who do not undergo surgery but are treated medically for CRS will also be enrolled to serve as a control group.
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- 16 Feb, 2024
- 1 location