Found 241 clinical trials
Leptospirosis Registry Gathers Knowledge on Epidemiology Clinical Course Prognostic Factors and Molecular Characteristics for Invasive Leptospirosis Disease
Incidence of invasive leptospirosis disease causing acute kidney injury, acute respiratory distress syndrome (ARDS), myocarditis, hepatic dysfunction, hemorrhage and multi-organ failure, is globally increasing and there have been frequent outbreak situation throughout the world. Due to increasing outbreak situations and globally chances in species distributions, a worldwide surveillance in epidemiology …
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- 16 Feb, 2024
- 1 location
AiCR : Artificial Intelligence in Cardiac aRrest
Also use of the algorithm to predict the risk of recurrence of the arrest, the duration of mechanical ventilation, the appearance of sepsis, the development of organ failure, prediction of the CPC (Cerebral Performance Category), time to obtain catecholamine withdrawal, the appearance of acute renal failure with or without the …
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- 05 Aug, 2020
Quality of Life and Physical Performance After Novel Coronavirus Infection (COVID-19);
This study aims to observe the long-term health-related quality of life (HRQOL) and physical performance in individuals hospitalized due to a COVID-19 infection. Therefore, data is extracted from a study-site standard aftercare program which has been adjusted for this patient population. This comprehensive aftercare program includes education sessions and physical …
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- 05 Aug, 2020
Lung CT Scan Analysis of SARS-CoV2 Induced Lung Injury
This is a multicenter observational retrospective cohort study that aims to study the morphological characteristics of the lung parenchyma of SARS-CoV2 positive patients identifiable in patterns through artificial intelligence techniques and their impact on patient outcome.
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- 16 Feb, 2024
- 8 locations
Genetics of COVID-19 Susceptibility and Manifestations
Some people who are infected with SARS-CoV-2 have mild symptoms or none at all. But others develop severe symptoms, like pneumonia or organ failure. Researchers think that people s genes might play a role in how sick they get. Researchers want to look at the genes of people who have …
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- 16 Feb, 2024
- 1 location
Application of Serial Body Composition Change for Risk Prediction in Treating Patients With Severe Pneumonia
We hypothesize that serial changes of body composition in patients with pneumonia can help clinician to monitor prognosis. It was associated with underlying immune response.
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- 16 Feb, 2024
- 1 location
Correlation Between Oxidative Stress Status and COVID-19 Severity
During the new COVID-19 pandemic physicians all over the world have faced different challenges .Oxidative stress is a probable cause of multi organ failure in this setting which never has been evaluated in COVID-19 infection to the best of knowledge.Present study aimed to evaluate oxidative stress marker and redox system …
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- 05 Aug, 2020
Imaging Feature of SARS-CoV2 Infection
The severity of the disease varies widely with evidence of mild disease in the majority of confirmed cases, severe pneumonia-dyspnea, hypoxia or lung involvement at imaging within 24-48 hours- and critical disease with respiratory failure, shock or multi-organ failure in particular patient cohorts. Imaging plays a key role is diagnosis …
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- 16 Feb, 2024
- 1 location
Acute Kidney Injury and Renal Outcomes for COVID-19 Patients in Intensive Care Units
The actual COVID-19 epidemy is an unprecedented healthcare problem. Although acute respiratory distress syndrome is the main organ failure, acute kidney injury (AKI) has appeared to be more frequent and more severe than expected. Some data suggested a potential direct renal tropism of the virus, or undirect injury by "cytokine …
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- 16 Feb, 2024
- 1 location
The Effect and Mechanism of lncRNA NBR2 Regulating Endothelial Pyroptosis by Targeting GSDMD in Sepsis
Sepsis is a life-threatening disease characterized by multi-organ failure due to dysregulated host response to infection, with high global mortality of 30-50%. One of the most important pathophysiologic hallmarks in sepsis is vascular endothelial injury that contributes to the severity and outcome of the syndrome.
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- 05 Aug, 2020