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Multicenter Perspective Study: Clinical Evaluation of the Persona MC With Preservation or Sacrifice of the PCL

Evaluation of clinical and radiographic outcomes in Italian patients undergoing total knee replacement with the Persona Medial Congruent implant with sacrifice or retention of the posterior cruciate ligament (PCL)

Physical Rehabilitation Evaluation and Optimal Physical Therapy (PRE-OPT)

Phase 1: The investigators will conduct a prospective study to quantify the association between axillary web syndrome (AWS) and metastatic disease and chronic morbidities such as lymphedema, shoulder dysfunction, and pain comparing women (i) with AWS and (ii) without AWS in two cohorts of women. (n=200) Phase 2: This is …

Postoperative Radiotherapy in Breast Cancer- Concurrent or Sequential With Chemotherapy (CONCERT)

What effects does concurrent treatment have on post-operative look, quality of life, and side effects including arm swelling (lymphoedema)?What are each treatment approach's financial costs?Researchers will compare the following to groups:Arm A: Participants in the sequential treatment group will first undergo chemotherapy and then radiation.