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Found 242 clinical trials
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Pharmacokinetics and Safety of SHR0302 in Patients With Hepatic Impairment

Study to Evaluate Pharmacokinetics and Safety of SHR0302 in Patients With Mild, Moderate Hepatic Impairment and Normal Liver Function in Phase I Clinical Study

body mass index
moderate hepatic impairment
moderate hepatic insufficiency
hepatic impairment
liver disease
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  • 16 Feb, 2024
  • 1 location
Study of Pexidartinib in Participants With Moderate Hepatic Impairment Compared With Healthy Participants

The pharmacokinetics of a single dose of pexidartinib will be investigated in participants with impaired hepatic function and compared with healthy control participants with normal hepatic function.

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  • 16 Feb, 2024
  • 2 locations
Study to Evaluate the Pharmacokinetics (PK) of E7090 and Its Metabolite in Participants With Mild and Moderate Hepatic Impairment Compared to Healthy Participants

The primary purpose of the study is to evaluate the effects of mild and moderate hepatic impairment on PK of E7090 after a single dose administration.

body mass index
moderate hepatic impairment
electrocardiogram
moderate hepatic insufficiency
e7090
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  • 16 Feb, 2024
  • 3 locations