Found 1830 clinical trials
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This is a randomized, open-label, parallel group study to determine the optimal dose of CART-19 cells (of the two dose levels being assessed (1-5x10xE8 vs. 1-5x10xE7 CART-19 cells). This trial will be conducted in two stages 123.
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- 23 Feb, 2023
Study in Healthy Adult Male Participants to Gather Information How the Human Body Absorbs Distributes and Excretes the Study Drug Selitrectinib Including the Effect of the Interaction of Food With the Study Drug on the Human Body
Participants in this study will receive the study drug twice with at least 6 days in between. The study drug will be taken orally as a liquid before or after meal. Observation will last for up to 8 weeks, and blood samples will be taken from the participants to measure …
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- 16 Feb, 2024
- 1 location
Phase I Study in Advanced Malignancies
RDT aims to take advantage of the relatively safer toxicity profiles of both lower dose radiation therapy and systemic ALA to treat non-superficial lesions in a manner similar to photodynamic therapy. The doses of radiation administered in this study will be lower than those typically used to treat cancer. However, …
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- 16 Feb, 2024
- 1 location
SubsTRate OxidatioN in Girls
This study will examine race differences in total energy expenditure and respiratory quotient (RQ) during and after exercise, compared to a sedentary control condition, in adolescent girls who are classified as overweight. In addition, subjective appetite will be measured throughout the assessment periods.
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- 16 Feb, 2024
- 1 location
A Study to Investigate the Pharmacokinetics Efficacy and Safety of INM005 in Patients With COVID-19.
Improvement of the clinical course 28 days after the start of treatment will be evaluated.
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- 16 Feb, 2024
- 6 locations
The Influence of a Perturbation Training on Balance Recovery of Old Adults: a Randomized Controlled Trial
We hypothesize that response to an unexpected loss of balance is the balance responses will be improved in both training methods, but more in the random training method. We also hypothesize that brain function as seen in MRI will be improved in both training methods, more in the random training …
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- 16 Feb, 2024
- 3 locations
COVID-19 Convalescent Plasma for the Treatment of Hospitalized Patients With Pneumonia Caused by SARS-CoV-2.
The purpose of this study is to see if this plasma can be safely used in humans with COVID-19 and to see if it improves patients' health as compared to not using it in patients with pneumonia caused by SARS-CoV-2.
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- 05 Aug, 2020
TACE Combined With PD-1 Knockout Engineered T Cell in Advanced Hepatocellular Carcinoma.
This study will evaluate the safety and effect of transcatheter arterial chemoembolization (TACE)combined with percutaneous transhepatic PD-1 knockout engineered T cell infusion in the Paitents with advanced hepatocellular carcinoma(HCC). Blood and tissue samples will also be collected for research purposes.
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- 05 Aug, 2020
Baseline Relative Peripheral Refraction in Myopia Control
At the lens dispensing and 2-week follow-up visits, vision acuity testing and computer scanning of posterior eyes will be measured. New DIMS lens will be replaced and upgraded if the equivalent sphere of refraction (SER) is changed or visual acuity change.
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- 08 Dec, 2023
- 1 location
High Volume Caudal Study
In addition, caudal clonidine's effect on length of recovery and post-operative emergence agitation will be measured.
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- 16 Feb, 2024
- 1 location