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Found 2528 clinical trials
Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis

Background Psoriasis causes chronic inflammation in the body. Researchers want to see if a kind of vitamin B3 dietary supplement can help. This might lead to more treatment options. Objective To test if the dietary supplement nicotinamide riboside can improve immune system function in the blood and skin of people …

chronic inflammation
nicotinamide
urine test
body mass index
niacin
  • 0 views
  • 16 Feb, 2024
  • 1 location
Feasibility and Effectiveness of Delivering Cognitive Behaviour Therapy Through Online Psychotherapy Tool (OPTT) for Depression

The purpose of this study is to determine the efficacy of e-CBT to treat depression through an online, module-based program. The study aims to determine if anxiety severity and symptomatology decreased after the administration of 12 e-CBT sessions delivered through OPTT. This study also aims to determine the difference in …

major depressive disorder
psychiatric disorder
depression
depressive disorder
psychotherapy
  • 0 views
  • 16 Feb, 2024
  • 1 location
Effect of Brain Stimulation on Stepping Performance in Stroke Survivors and Healthy Adults

Participants are being asked to participate in a research study conducted by Shih-Chiao Tseng, PT, Ph.D. at Texas Woman's University. This research study is to determine whether low-intensive brain stimulation can enhance learning of a leg movement task. The investigators also want to know if brain stimulation can improve the …

transcranial direct current stimulation
mini-mental state examination
hemiparesis
brain stimulation
range of motion exercise
  • 0 views
  • 16 Feb, 2024
  • 1 location
Taiwan "Aerosol Box" Versus UMMC "Intubation Box"

This study compares two intubation boxes, that is the Taiwan "Aerosol Box" versus the UMMC "Intubation Box". The importance of this intubation box has come to light recently in view of the COVID-19 pandemic and the fact that intubation is an aerosol-generating procedure. Risks of the healthcare worker attending to …

covid-19
intubation
  • 0 views
  • 05 Aug, 2020
Characterization of Chewing and Swallowing and Verification of the Effectiveness of Orofacial Motricity Stimulation in Severe Obese Pre and Post Bariatric Surgery: a Randomized Controlled Clinical Trial.

Background: Obesity is considered an epidemic disease of great repercussion on the world and its prevalence has increased in recent decades. The treatment of obesity aims to improve health and quality of life, by reducing body weight. The clinical approach to obesity is routinely the first line of treatment. Clinical …

Accepts healthy volunteers
  • 0 views
  • 07 Sep, 2022
  • 2 locations
Respiratory Muscle Training (RMT) in ALS

Twelve adults with ALS will participate in a study involving four 3-week cycles of progressive respiratory muscle training (RMT). The investigators will measure maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP) weekly. The investigators will obtain the majority of measurements of MIP and MEP during web-based telehealth visits. Participants …

maximum expiratory pressure
weakness
maximum inspiratory pressure
respiratory muscle training
  • 0 views
  • 16 Feb, 2024
  • 1 location
Empowering Patients to Participate in Health Care Decisions

The study aims to evaluate whether an intervention with patient education in study circles, aiming to empower patients to participate in health care an rehabilitation by increasing health literacy and sense of coherence, may have a causal effect on perceived health, ability and function as well as independence and quality …

  • 0 views
  • 16 Feb, 2024
  • 1 location
Lorlatinib Combinations in Lung Cancer

This research study is evaluating Lorlatinib in combination with Crizotinib or Binimetinib as a possible treatment for either anaplastic lymphoma kinase (ALK)-positive lung cancer or ROS1-positive lung cancer. This research study involves three study drugs. Lorlatinib Binimetinib Crizotinib

tyrosine
alk gene translocation
seizure
small cell lung cancer
traumatic injury
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Ablation of Fibrotic Areas in Patients With Persistent Atrial Fibrillation.

Brief summary: The objective of this study is to compare two different ablation strategies in participants with persistent atrial fibrillation and fibrotic areas in the left atrium. The participant will be randomized to pulmonary vein isolation or pulmonary vein isolation plus ablation of fibrotic areas.

fibrillation
antiarrhythmic drug
atrial fibrillation
catheter ablation
radiofrequency ablation
  • 0 views
  • 16 Feb, 2024
  • 1 location
Safety of Minimally Invasive Surgery Using Endoscopic Stapler in Early Stage Cervical Cancer Patients (SOLUTION)

The SOLUTION trial aims to show the efficacy and safety of performing radical hysterectomy by minimally invasive surgery using an endoscopic stapler in patients with cervical cancer stage IB1 (FIGO staging 2009) and thus to prove that minimally invasive surgery is non-inferior to open surgery.

cancer
adenosquamous carcinoma
carcinoma
cervical disease
squamous cell carcinoma
  • 0 views
  • 16 Feb, 2024
  • 1 location