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Found 2528 clinical trials
Post-surgical Liquid Biopsy-guided Treatment of Stage III and High-risk Stage II Colon Cancer Patients: the PEGASUS Trial

PEGASUS is a prospective multi-centric study designed to prove the feasibility of using liquid biopsy to guide the post-surgical and post-adjuvant clinical management in 140 microsatellite stable Stage-III and T4N0 Stage-II colon cancer patients.

endoscopy
ffpe
adjuvant
folfiri regimen
capecitabine
  • 0 views
  • 16 Feb, 2024
  • 9 locations
Balloon Lithoplasty for Preparation of Severely Calcified Coronary Lesions

Severely calcified coronary stenoses are difficult to treat with percutaneous coronary intervention (PCI) using current techniques and there is little specific evidence on how to best treat these cases. It is hypothesized that balloon lithoplasty is superior to conventional balloons for lesion preparation of severely calcified coronary lesions before stent …

coronary disease
exercise test
ischemia
coronary artery stenosis
stenosis
  • 0 views
  • 16 Feb, 2024
  • 6 locations
Reinforced PTFE Meshes Versus Customized Titanium Meshes

The objective of this study is to compare two surgical techniques for the treatment of the maxillary and mandibular bone atrophies.. Therefore, the main purpose is to compare the (i) the percentage of post-operative complications (ii) the three-dimensional bone gain with customized titanium meshes (test group - the medical device …

partial edentulism
  • 0 views
  • 16 Feb, 2024
  • 1 location
Shortened Antibiotic Treatment of 5 Days in Gram-negative Bacteremia

GNB5 is an investigator-initiated multicentre non-inferiority randomized controlled trial which aims to assess the efficacy and safety of shortened antibiotic for patients hospitalized with a Gram negative bacteremia with a urinary tract source of infection (GNB). Five days after initiation of antimicrobial therapy for GNB, participants are randomized 1:1 to …

  • 0 views
  • 16 Feb, 2024
  • 12 locations
tDCS Intervention on Motivational Anhedonia of Major Depressive Disorder

Study of tDCS intervention on motivational anhedonia of Major Depressive Disorder

depression
major depressive disorder
depressive disorder
antidepressants
anhedonia
  • 0 views
  • 16 Feb, 2024
  • 1 location
Safety Tolerability and Pharmacokinetics of Inhaled Nanoparticle Formulation of Remdesivir (GS-5734) and NA-831

The clinical study is designed to evaluate the safety, tolerability and pharmacokinetics of inhaled nanoparticle nanoparticle formulation of Remdesivir (GS-5734) alone and in combination with NA-831 in 48 healthy volunteers.

hepatitis b surface antigen
tubal ligation
hepatitis c
immunodeficiency
hysterectomy
  • 0 views
  • 16 Feb, 2024
  • 1 location
Cocoa/Carob Polyphenols and Postprandial Changes in Type 2 Diabetes

The aim of this is study is to evaluate the effects of a single intake of a mixture of cacao and carob (rich in high molecular weight polyphenols) in postprandial metabolism in subjects with type 2 diabetes. Studies on the effects of polyphenols on postprandial (glucidic and lipidic) metabolism have …

polyphenol
metformin
  • 0 views
  • 16 Feb, 2024
  • 1 location
Stay Well at Home: a Text-messaging Study Social Distancing

The investigators have developed supportive text-messages in English and Spanish to help people cope with the stress and anxiety of COVID-19 social distancing. The purpose of this study is to examine if automated text-messages will improve depression and anxiety symptoms and enhance positive mood. Additionally, the investigators will compare the …

anxiety
depression
anxiety symptoms
covid-19
  • 0 views
  • 16 Feb, 2024
  • 1 location
Meditation and Kundalini Yoga for Heightened Anxiety Related to COVID-19

This randomized clinical on-line study examines whether whether a daily practice of meditation or Kundalini Yoga with anxiety reduction training leads to a greater reduction in anxiety than anxiety reduction training alone.

  • 0 views
  • 05 Aug, 2020
Irreversible Electroporation of Unresectable Liver Tumors

The aim of this study is to evaluate the safety and feasibility of curative intended irreversible electroporation (IRE) in the treatment of liver tumors neighboring major vessels or bile ducts.

metastasis
biliary tract cancer
irreversible electroporation
cancer
liver tumor
  • 0 views
  • 05 Aug, 2020