Found 238 clinical trials
COVID-19 and Cancer Patients
Routinely collected data will be used to assess the morbidity and mortality of cancer patients following a positive COVID-19 infection.
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- 01 Feb, 2023
- 1 location
Genetics of COVID-19 Susceptibility and Manifestations
Background The current SARS-CoV-2 pandemic presents a serious challenge to public health. Some people who are infected with SARS-CoV-2 have mild symptoms or none at all. But others develop severe symptoms, like pneumonia or organ failure. Researchers think that people s genes might play a role in how sick they …
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- 16 Feb, 2024
- 1 location
A Study to Identify Errors in Inhaler Technique in Adults
This study will observe the inhaler technique of people using 13 different inhaler types; record any technique errors being made against checklists developed for each inhaler device based on their manufacturer's guidelines, and reeducate any observed inhaler technique errors as required.
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- 16 Feb, 2024
- 1 location
RASopathy Biorepository
The RASopathies are a group of developmental disorders caused by genetic changes in the genes that compose the Ras/mitogen activated protein kinase (MAPK) pathway. New RASopathies are being diagnosed frequently. This pathway is essential in the regulation of the cell cycle and the determination of cell function. Thus, appropriate function …
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- 05 Aug, 2020
Inhaled Corticosteroid Withdrawal in Chronic Obstructive Pulmonary Disease (COPD)
According to the WISDOM study, withdraw of inhaled steroids has no effect on the acute exacerbation of chronic obstructive pulmonary disease (COPD), but the lung function of patients with COPD is significantly reclined. In the subgroup analysis of this study, patients with COPD were found to have continued to use …
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- 05 Aug, 2020
The Real World Study of Neoadjuvant Immunotherapy in Early Stage NSCLC in China
Several published clinical trials have shown the superiority of immunotherapy in neoadjuvant setting. Here we conducted this real world study to see whether neoadjuvant immunotherapy would bring MPR and survival benefits in NSCLC, for example, single agent immunotherapy or immunotherapy combination with chemotherapy. Furthermore biomarker analysis would be also performed …
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- 16 Feb, 2024
- 1 location
Classification of Benign and Malignant Lung Nodules Based on CT Raw Data
The employ of medical images combined with deep neural networks to assist in clinical diagnosis, therapeutic effect, and prognosis prediction is nowadays a hotspot. However, all the existing methods are designed based on the reconstructed medical images rather than the lossless raw data. Considering that medical images are intended for …
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- 16 Feb, 2024
- 1 location
Evaluation of Eosinophil Phenotype in COPD Patients
Aim of the study is to analyze the immunophenotype of circulating eosinophils in chronic obstructive pulmonary disease (COPD) patients, and to correlate results with clinical status of patients (stable versus exacerbated patients, response to therapy).
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- 16 Feb, 2024
- 1 location
CT-based Radiomic Algorithm for Assisting Surgery Decision and Predicting Immunotherapy Response of NSCLC
The purpose of this study was to investigate whether the combined radiomic model based on radiomic features extracted from focus and perifocal area (5mm) can effectively improve prediction performance of distinguishing precancerous lesions from early-stage lung adenocarcinoma, which could assist clinical decision making for surgery indication. Besides, response and long …
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- 05 Aug, 2020
Immunotherapy in Lung Cancer: Treatment After IO Cessation.
Immunotherapy is now a standard of care for first-line and eventually salvage therapy in patients with stage IV NSCLC and as adjuvant after RT-CT for stage III NSCLC. The aim of the study is determining the therapeutic landscape and the reason for immunotherapy cessation.
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- 05 Aug, 2020