Found 21 clinical trials
A Rhinovirus Challenge Study to Investigate Exacerbations and Immune Responses in Bronchiectasis (BARRIER)
The goal of this study is to determine if viral infection with the common cold leads to an exacerbation in participants with bronchiectasis. We will compare the participants with bronchiectasis to a group of healthy participants. The main questions it aims to answer are:Does viral infection with the common cold …
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- 23 Apr, 2025
- 1 location
A Home-based Physical Activity Programme for Patients With Advanced Interstitial Lung Diseases (iLiFE)
Interstitial lung diseases (ILD) are a highly incapacitating group of chronic respiratory diseases, leading to disabling symptoms and impaired capacity to perform activities of daily living and health-related quality of life (HRQoL). It is known that people with ILD are highly inactive and sedentary, and in a severe stage of …
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- 16 Feb, 2024
- 1 location
Direct and Indirect Impact of COVID-19 In Older Populations
This study propose to describe risk factors for acute and long term mortality of COVID 19 in patients up to 70 years old.
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- 05 Aug, 2020
Daytime Sleepiness in Patients With the Assessment of a Sleep-related Respiratory Disorder
It is not yet known whether an analysis of daytime sleepiness over the course of the day can predict the diagnosis or severity of sleep apnea. The goal of the study is to examine whether a psychometric determination of daytime sleepiness can adequately and practicably record daytime sleepiness in patients …
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- 05 Aug, 2020
A Study to Identify Errors in Inhaler Technique in Adults
This study will observe the inhaler technique of people using 13 different inhaler types; record any technique errors being made against checklists developed for each inhaler device based on their manufacturer's guidelines, and reeducate any observed inhaler technique errors as required.
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- 16 Feb, 2024
- 1 location
A Study of Patients With Chronic Disease
TARGET-RWE is a 10-year, international, longitudinal, observational study of patients with chronic disease designed to specifically address important clinical questions that remain incompletely answered from registration trials. The protocol will follow a master protocol design in which a shared study infrastructure supports progressive development of the registry across the spectrum …
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- 16 Feb, 2024
- 4 locations
The Multi-Ethnic Lifestyle Study
The study design is cross-sectional using a self-completion questionnaire in an English speaking multi-ethic population within Leicester and Leicestershire. The study will adopt a convenient and purposive sampling recruitment strategy across a variety of settings within Leicestershire to facilitate recruitment of a wide range of participants.
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- 16 Feb, 2024
- 1 location
A Clinical Study to Map the HLA Genomic Region in the Greek Population (GENESIS)
The aim of GENESIS clinical study is to map the HLA genomic region in the Greek population and evaluate possible correlations with selected underlying diseases.
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- 29 Jan, 2024
- 3 locations
AKI Biomarkers in Coronavirus(COVID)-19
This research aims to investigate the role of daily measurement of urinary cell cycle arrest markers and other serum and urinary biomarkers to predict the development of acute kidney injury in critically ill patients with COVID-19 and acute respiratory disease.
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- 05 Aug, 2020
Effects on the Qt Interval of COVID-19 Coronavirus Infection
The present study aims to evaluate the impact of COVID-19 disease and its treatment on ventricular repolarization, assessed by measuring the QTc interval, in patients admitted to the critical care unit.
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- 16 Feb, 2024
- 1 location