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Found 14 clinical trials
Rigosertib Plus Nivolumab for KRAS+ NSCLC Patients Who Progressed on First-Line Treatment

A Phase1/2a Study of Rigosertib plus Nivolumab in Stage IV Lung Adenocarcinoma Patients with KRAS Mutation who Progressed on First-Line Treatment

metastatic lung adenocarcinoma
cancer
rigosertib
measurable disease
tubal ligation
  • 0 views
  • 16 Feb, 2024
  • 1 location
Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers

This clinical trial is studying two immunotherapy drugs (nivolumab and ipilimumab) given together as a possible treatment for INI1-negative tumors.

cancer
kidney function tests
sarcoma
blood transfusion
samarium
  • 0 views
  • 05 Aug, 2020
Study to Assess the Efficacy and Safety of Nivolumab in Combination With Paclitaxel in Subjects With Head and Neck Cancer Unable for Cisplatin-based Chemotherapy (NIVOTAX)

This randomized phase II study will evaluate the efficacy of nivolumab plus paclitaxel for first-line treatment of recurrent or metastatic HNSCC in the platinum ineligible and platinum refractory settings.

cancer
squamous cell carcinoma of unknown primary
kidney function tests
liver metastasis
vitiligo
  • 0 views
  • 16 Feb, 2024
  • 20 locations
Concurrent Chemoradiation and Durvalumab for Locoregionally Advanced Nasopharyngeal Carcinoma

The investigators propose a phase II randomized-controlled study on using durvalumab in combination with induction chemotherapy followed by concurrent chemoradiation and adjuvant durvalumab, compared to induction chemotherapy followed by concurrent chemoradiation for previously untreated locoregionally advanced stage III to IVA NPC. In parallel, the investigators will also perform collateral tumor …

cancer
irreversible toxicity
corticosteroids
bilateral salpingectomy
adjuvant
  • 0 views
  • 05 Aug, 2020