Found 24 clinical trials
Early Environmental and Maternal Determinants of Airway Inflammation in Wheezing Disorders in Infants
This study collects data on microbiological, genetic and environmental factors, as well as lung function parameters (e.g. spirometry, body plethysmography, lung-MRI) to assess the complex interaction of predisposing risk factors for impaired lung development and respiratory diseases.
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- 16 Feb, 2024
- 1 location
Gut Microbiota and Alzheimer's Diseases
The investigator will perform clinical studies to test the hypothsis that participants who had Alzhemer's disease will have different gut microbiota in the feaces as compared to participants who did not have Alzhemer's disease, as well as compared to their spouse.The investigators plan to perfoem the studies in 150 participants …
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- 16 Feb, 2024
- 1 location
Lung Microbiota Analysis in Critically Ill Patients Admitted to the Intensive Care Unit.
Our study aims to evaluate the relationship between the heterogeneity of pulmonary microbiota and clinical and outcome variables among critically ill patients admitted to the intensive care unit (ICU). In patients undergoing invasive mechanical ventilation, an aliquot of bronchoalveolar lavage (BAL) fluid will be used in the microbiology laboratory for …
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- 16 Feb, 2024
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The Impact of Gut Microbiota in Anastomoses Insufficiency After Resection and Direct Anastomosis for Colorectal Cancer.
The role of gut microbiota in anastomosis insufficiency in patients operated for colorectal cancer and for peritoneal carcinomatosis is going to be investigated.
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- 16 Feb, 2024
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Development of Systems and Precision Medicine - Take Mood Disorder as an Example.
In this three-year proposal, we explore the interactions of genetic variants and environmental factors (represented by psychosocial stress and gut microbiota) driven approaches to develop precision medicine.
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- 16 Feb, 2024
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Study of the Discriminating Power of a Blood Biomarker for Omega-3 Polyunsaturated Fatty Acid Content of the Retina for Age-related Macular Degeneration (AMD)
For this purpose, the status of the subjects with regard to their intestinal flora (microbiota) will be evaluated. The relationship between lipid metabolism, microbiota and age-related macular degeneration should also provide a better understanding of the pathophysiological mechanisms that link diet, lipid metabolism and age-related macular degeneration.
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- 16 Feb, 2024
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Gut Microbiome in Biliary Atresia
The establishment of gut-liver axis, featured by cholangitis and gut-microbiome will open new pathway to treat the BA using fecal microbiota transplantation. Analysis of gut-microbiome: The investigator will investigate the alteration of gut-microbiome by restoration of bile flow at diagnosis, before and after Kasai procedure.
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- 16 Feb, 2024
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Clinical and Molecular Study of Endometriosis and Adenomyosis
We also aimed to address molecular questions on immune dialogues between ectopic lesions and the eutopic endometrium, auto-immunity in endometriosis and adenomyosis and the role of the microbiota in their respective pathophysiologies.
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- 16 Feb, 2024
- 1 location
Dynamics of the Urinary Bacterial Microbiota (DAIQUIRI)
It has thus been suggested that, following a disruption in the homeostasis of the urinary microbiota (urinary dysbiosis), certain bacteria considered commensals of the urinary tract can become pathogenic and lead to UTIs (Gerges-Knafl et al., 2020).
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- 16 Jun, 2025
Trajectory of Microbiota Maturation in Healthy Bern Infants - a Network Approach
Background: Intestinal microbiota composition is fundamental to human health and undergoes critical changes within the first two years of life. Factors probably influencing the microbiota are the maternal microbiota and the general environment in Switzerland.
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- 16 Feb, 2024
- 1 location