Found 20 clinical trials
Ketamine or Placebo in Patients With Major Depression and Advanced Cancer
Major depression (MD) is a psychiatric disorder characterized by a persistent feeling of sadness, anhedonia or a decreased perception of pleasurable experiences, as well as appetite alterations and weight variations, sleep disorders, altered psychomotor skills, fatigue, guilt, decreased self-worth, suicidal thoughts and difficulty concentrating in a task (1).
- 0 views
- 16 Feb, 2024
- 1 location
RCT for Electroconvulsive Treatment Followed by Cognitive Control Training
Major depressive disorder (MDD) is worldwide one of the most prevalent and disabling mental health conditions. Electroconvulsive therapy (ECT) is a safe and effective treatment even though 6-month relapse rates are high.
- 0 views
- 05 Aug, 2020
Mechanism of Action of Transcranial Magnetic Stimulation
This is an observational neuroimaging study assessing the effects of TMS on the brains of patients with unipolar depression.
- 0 views
- 16 Feb, 2024
- 1 location
Accelerated iTBS for Depressed Patients During the COVID-19 Pandemic
The current study aims to assess the feasibility, acceptance and clinical outcomes of a practical high-dose aiTBS protocol, including tapering treatments and symptom-based relapse prevention treatments, in patients with unipolar depression previously responsive to ECT and patients needing urgent treatment due to symptom severity during the COVID-19 pandemic.
- 0 views
- 16 Feb, 2024
- 1 location
High Dose Accelerated iTBS for Depression
This trial will compare active intermittent theta burst stimulation (iTBS) rTMS in an accelerated treatment schedule (8 treatment sessions per day for 5 days) to a placebo control. Depression symptom severity will be measured before, during, at end of treatment, 1-week post and 4-weeks post treatment.
- 0 views
- 16 Feb, 2024
- 3 locations
Open-label Flexible-dose Study of Vortioxetine in Patients With Depression in India
The purpose of this study is to evaluate the safety and tolerability of flexible doses of vortioxetine (5 - 20 mg/day) over a period of 12 weeks in patients with depression in India
- 0 views
- 16 Feb, 2024
- 8 locations
Feasibility and Effectiveness of Delivering Cognitive Behaviour Therapy Through Online Psychotherapy Tool (OPTT) for Depression
The purpose of this study is to determine the efficacy of e-CBT to treat depression through an online, module-based program. The study aims to determine if anxiety severity and symptomatology decreased after the administration of 12 e-CBT sessions delivered through OPTT. This study also aims to determine the difference in …
- 0 views
- 16 Feb, 2024
- 1 location
iTBS for Adolescent Depression: An Open Label Study Evaluating Safety and Efficacy of Treatment
This is an open label, pilot, feasibility study evaluating effects of Intermittent Theta Burst Transcranial Magnetic Stimulation (iTBS) on 5 eligible adolescents for the treatment of depression. Safety and tolerability will be evaluated with changes in depression scores, and suicidality and non-suicidal self injurious behavior will also be monitored for …
- 0 views
- 05 Aug, 2020
Combining H1-Coil Deep Transcranial Magnetic Stimulation (dTMS) and App-guided CBT in Subjects With Major Depression Disorder (MDD)
A naturalistic study design, in which dTMS patients will be randomized to get a free add-on CBT treatment. The dTMS procedure will include treatment as usual, and participants will use the app from post randomization (Pre-treatment is defined as measures from the first three days of treatment) to the end …
- 0 views
- 16 Feb, 2024
- 22 locations
A Study to Describe Routine Treatment Pathways in Participants With Major Depression and Active Suicidal Ideation With Intent in Italy
The purpose of the study is to describe the pharmacological and non-pharmacological treatment utilization pathways in Italian routine clinical practice of participants with Major Depressive Disorder (MDD) and active suicidal ideation with intent.
- 0 views
- 05 Aug, 2020
- 1 location
- 1
- 2