Found 28 clinical trials
2-Hydroxybenzylamine (2-HOBA) to Prevent Early Recurrence of Atrial Fibrillation After Catheter-based Ablation
The proposed studies will test this hypothesis by randomizing patients with AF to 2-HOBA or placebo 7 days prior to AF ablation to allow 2-HOBA to reach steady-state levels. We hypothesize that tissue injury from AF ablation causes a large release of ROS that react with lipids to generate IsoLGs …
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- 05 Aug, 2020
Assessment of Paravalvular Leak After TAVI by Hemodynamic Measurements and Cardiac MRI
Rationale: Transcatheter aortic valve implantation (TAVI) has become the standard therapy for elderly patients with high surgical risks. Paravalvular leakage after TAVI is relatively common and there is conflicting evidence regarding the clinical impact of mild paravalvular leakage in self-expanding devices. Prospective data for self-expanding devices are required to compare …
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- 16 Feb, 2024
- 1 location
SeQuent Please Neo Multicenter Registry
The registry evaluates the safety and efficacy of paclitaxel-releasing SeQuent Please Neo balloon in the following scenarios: restenosis, bifurcation lesions, small vessel lesions, diabetes (diffuse disease) and atrial fibrillation. The objective is to determine the success of the procedure and the preservation of vascular permeability.
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- 16 Feb, 2024
- 1 location
Computer-based Online Database of Acute Stroke Patients for Stroke Management Quality Evaluation
In the past three decades, the burden of stroke has increased in China and has gradually become the leading cause of death. The data acquisition and medical quality management still need to be improved in China. The purpose of this study was to establish online database of acute stroke patients …
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- 16 Feb, 2024
- 1 location
Atrial Fibrillation After PFO Closure
An increased risk of atrial fibrillation (AF) after patent foramen ovale (PFO) closure was observed in randomized trials but systematic screening of AF was not performed in these studies.
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- 16 Feb, 2024
- 1 location
The Impact of Frailty on Thrombosis of Elderly Patients With NVAF FTE-NVAF
This study aims to investigate the use of anticoagulants in elderly patients with non-valvular atrial fibrillation (NVAF) and the incidence of frailty in elderly patients with NVAF. After two years follow-up, we observe the incidence of thrombotic events and the influence of frailty on thrombotic events in elderly patients with …
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- 16 Feb, 2024
- 1 location
Validity Test of Wearable Continuous Blood Pressure Measuring System
Criteria of Participant Inclusion Adult patient in surgical intensive care of Severance Hospital Voluntarily agreed to participate the research and not included to the exclusion criteria Criteria of Participant Exclusion Patient with occlusive peripheral arterial disease Patient with cardiovascular disease of serious arrhythmia except atrial fibrillation Patient administered high-dose of …
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- 16 Feb, 2024
- 1 location
Comparison of Cardiac Function Between Left Bundle Branch Pacing and Right Ventricular Outflow Tract Septal Pacing in Pacemaker-dependent Patients
Permanent pacemaker implantation is a common method for bradycardia and cardiac conduction dysfunction. With the development of physiological pacing, the optimal location of ventricular pacing site is still improving. Traditional ventricular pacing site at the apex of right ventricle or septum of right ventricular outflow tractRVOT, causing iatrogenic left bundle …
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- 16 Feb, 2024
- 1 location
Determination of Diastolic Dysfunction by Single Lead Electrocardiogram
It is a prospective, controlled, single-center, non-randomized, observational study. From September 2019 to December 2020, the study plans to prospectively include 400 patients aged 18 to 90 years. Every patients will undergo an echocardiographic examination with assessment diastolic dysfunction of the left ventricle, and registration of an electrocardiogram using a …
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- 16 Feb, 2024
- 1 location
Indonesian Registry on Atrial Fibrillation
Our rationale of creation of this registry stems from the fact that the use of VKA in patients with AF is a double-edged sword, physicians face tremendous burden in assigning patients with VKA, due to risk of Bleeding complications despite its potential benefit. We intend to seek a safe and …
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- 16 Feb, 2024
- 25 locations