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Found 14 clinical trials
Bioequivalence and the Tolerability and Antitumor Activity of Selinexor Combination Treatment

During the Combination Therapy Period, the safety and preliminary anti-tumor activity of selinexor in combination with docetaxel (for patients with NSCLC) or pembrolizumab (for patients with CRC) will be evaluated.

docetaxel
moderate hepatic impairment
pembrolizumab
carcinoma
programmed cell death protein 1
  • 0 views
  • 16 Feb, 2024
  • 3 locations
Nedaplatin Versus Cisplatin in Treatment for Nasopharyngeal Carcinoma

To compare the effectiveness and toxicity of nedaplatin versus cisplatin in induction chemotherapy combined with concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma.

docetaxel
concurrent radiochemotherapy
nedaplatin
nasopharyngeal carcinoma
renal function test
  • 0 views
  • 16 Feb, 2024
  • 1 location
Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

This is a Phase 1b/2, open-label, multicenter platform trial to evaluate the antitumor activity and safety of AB928-based combination therapy in participants with metastatic castrate resistant prostate cancer (mCRPC).

measurable disease
docetaxel
prostate cancer
taxane
antiandrogen therapy
  • 0 views
  • 16 Feb, 2024
  • 22 locations
Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharyngeal Cancer.

The objective of this trial is to study the efficacy of treatment of human papilloma virus (HPV) related oropharyngeal cancer with chemotherapy followed by Transoral Robotic Surgery (TORS) as definitive treatment. Current treatment of oropharyngeal cancer are chemo-radiotherapy. There is significant lifelong side effects associated with this approach related to …

docetaxel
oropharyngeal
carcinoma
absolute neutrophil count
karnofsky performance status
  • 0 views
  • 16 Feb, 2024
  • 1 location