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Found 14 clinical trials
Bioequivalence and the Tolerability and Antitumor Activity of Selinexor Combination Treatment

During the Combination Therapy Period, the safety and preliminary anti-tumor activity of selinexor in combination with docetaxel (for patients with NSCLC) or pembrolizumab (for patients with CRC) will be evaluated.

stage iv non-small cell lung cancer
monoclonal antibody therapy
colorectal cancer
systemic therapy
monoclonal antibodies
  • 0 views
  • 16 Feb, 2024
  • 3 locations
Nedaplatin Versus Cisplatin in Treatment for Nasopharyngeal Carcinoma

To compare the effectiveness and toxicity of nedaplatin versus cisplatin in induction chemotherapy combined with concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma.

karnofsky performance status
chemoradiotherapy
concurrent radiochemotherapy
cisplatin
metastasis
  • 0 views
  • 16 Feb, 2024
  • 1 location
Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

This is a Phase 1b/2, open-label, multicenter platform trial to evaluate the antitumor activity and safety of AB928-based combination therapy in participants with metastatic castrate resistant prostate cancer (mCRPC).

measurable disease
prostatic neoplasm
taxane
prostatic neoplasms, castration-resistant
testosterone
  • 0 views
  • 16 Feb, 2024
  • 22 locations
Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharyngeal Cancer.

The objective of this trial is to study the efficacy of treatment of human papilloma virus (HPV) related oropharyngeal cancer with chemotherapy followed by Transoral Robotic Surgery (TORS) as definitive treatment. Current treatment of oropharyngeal cancer are chemo-radiotherapy. There is significant lifelong side effects associated with this approach related to …

neck dissection
neutrophil count
primary tumor
definitive treatment
docetaxel
  • 0 views
  • 16 Feb, 2024
  • 1 location