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Found 138 clinical trials
Study of a Novel Multicomponent Meningococcal Group B Vaccine When Given Alone or With Other Licensed Vaccines in Adults, Adolescents, Toddlers and Infants

Primary Objective:To describe the safety profile of the SP MenB vaccine formulations and the 2 licensed MenB comparator vaccines in healthy adults, adolescents, toddlers and infants, when administered alone (Stages 1-4) or concomitantly with MenQuadfiTM (MenACYW conjugate vaccine) (for Stages 2-4 only), and with age-appropriated routine pediatric vaccines (for Stages …

  • 0 views
  • 13 Sep, 2023
  • 23 locations
Study of a Novel Multicomponent Meningococcal Group B Vaccine When Given Alone or With Other Licensed Vaccines in Adults, Adolescents, Toddlers and Infants

Primary Objective:To describe the safety profile of the SP MenB vaccine formulations and the 2 licensed MenB comparator vaccines in healthy adults, adolescents, toddlers and infants, when administered alone (Stages 1-4) or concomitantly with MenQuadfiTM (MenACYW conjugate vaccine) (for Stages 2-4 only), and with age-appropriated routine pediatric vaccines (for Stages …

  • 0 views
  • 06 May, 2024
  • 6 locations
Gas Tamponade for Prevention of Postoperative Vitreous Hemorrhage in Diabetics

Subjects undergo vitreous substitution with either SF6 gas or fluid during vitrectomy.

diabetes
vitreous hemorrhage
vitrectomy
  • 0 views
  • 05 Aug, 2020
Study of Safety Tolerability and PK PD of HPG1860 in Healthy Subjects

This is a randomized, double-blind, placebo-controlled, single and multiple ascending dose Phase 1study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and food effect of HPG1860 orally administered in healthy subjects.

  • 0 views
  • 16 Feb, 2024
  • 1 location
A Clinical Trial of Convalescent Plasma Compared to Best Supportive Care for Treatment of Patients With Severe COVID-19

This is a randomized, prospective, multicenter, open label clinical trial of convalescent plasma compared to best supportive care for treatment of patients with severe COVID-19. The aim of the study is to explore the therapeutic effect of convalescent plasma transfusions on the survival and course of disease of patients with …

plasma transfusion
covid-19
acute respiratory syndrome (sars)
SARS
  • 0 views
  • 16 Feb, 2024
  • 3 locations
Apomorphine Pump in Early Stage of Parkinson's Disease (EARLY-PUMP)

The aim of the study is to assess the use of the apomorphine pump in earlier stages of Parkinson' Disease (PD), when motor complications have just developed and before patients are significantly affected in their social and occupational functioning. The investigators hypothesize that apomorphine pump is superior in terms of …

parkinsonism
medical therapy
dyskinesia
apomorphine
  • 0 views
  • 16 Feb, 2024
  • 21 locations
A Study of the Safety and Efficacy of Ciclesonide in the Treatment of Non-hospitalized COVID-19 Patients

The purpose of this study is to assess the safety and efficacy of Alvesco (ciclesonide) Inhalation Aerosol in non hospitalized patients with symptomatic COVID-19 infection in a multicenter, randomized, double-blind, placebo controlled study

ciclesonide
inhalation technique
hydroxychloroquine
fever
cystic fibrosis
  • 0 views
  • 05 Aug, 2020
Decitabine+Cladribine+Cytarabine+Granulocyte Colony-stimulating Factor (D-CLAG) for Relapsed or Refractory Acute Myeloid Leukemia (AML)

A prospective, single-arm, multicenter, exploratory study to evaluate the efficacy and safety of D-CLAG regimen in the treatment of relapsed or refractory acute myeloid leukemia

refractory acute myeloid leukemia (aml)
decitabine
glomerular filtration rate
leukemia
clag regimen
  • 0 views
  • 17 Feb, 2024
  • 1 location
Methylene Blue in Early Septic Shock

Septic shock is a subset of sepsis characterized by a decrease in vascular tone, which contributes to impaired regional blood flow distribution, and leads to organic failure. Besides intravenous fluids and adequate antimicrobial therapy, patients with septic shock require vasopressor support, which can lead to many adverse effects, therefore, non-vasopressor …

antibiotics
antibiotic therapy
shock
sepsis
norepinephrine
  • 0 views
  • 05 Aug, 2020