Found 123 clinical trials
Acceptance and Commitment Therapy for PTSD and Chronic Pain
The primary aim of this study is to investigate the effect of Internet-delivered Acceptance and commitment therapy for PTSD and comorbid chronic pain using a randomized controlled trial with waitlist control.
- 0 views
- 06 Nov, 2025
- 2 locations
A Medical Research Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients
To evaluate the effect of venglustat on mood using Beck Depression Inventory II (BDI-II) (Stages 1 and 2). To evaluate the effect of venglustat on the lens by ophthalmological examination (Stages 1 and 2).
- 0 views
- 04 Dec, 2020
- 81 locations
ESM-derived Personalised Feedback for Women at Risk of Depression
This study aims to examine the effectiveness of Experience Sampling Method (ESM) derived personalised feedback for women at risk of depressive disorder in Hong Kong, in reducing individuals depressive symptoms.
- 0 views
- 16 Feb, 2024
- 1 location
Culturally Centered CBT for Latinx Youth
The primary aim of the proposed research is to test the effect of a culturally centered treatment protocol, the Socio-cognitive behavioral therapy (SCBT), versus Treatment as Usual on suicidal thoughts and attempts, and depressive symptoms, in a clinical sample of Latinx adolescents. The study is trying to determine, if we …
- 0 views
- 16 Feb, 2024
- 2 locations
A Home-based Study Using Mobile Technology to Test Whether BI 1358894 is Effective in People With Depression
The main objectives of this trial are to evaluate the efficacy and safety of oral BI 1358894 compared to placebo over a 6-week treatment period in participants with Major Depressive Disorder (MDD) and with inadequate response to antidepressants (SSRI or SNRI) utilizing a decentralized clinical trial (DCT) model.
- 0 views
- 16 Feb, 2024
- 1 location
A Study of Oral Seltorexant as an add-on Medication to an Antidepressant on On-road Driving Performance in Participants With Major Depressive Disorder
The purpose of the study is to evaluate the effect of seltorexant, compared to placebo, as an add-on medication to an antidepressant, on next-day driving performance as assessed by the mean difference of standard deviation of lateral position (SDLP) from an on-road driving test.
- 0 views
- 16 Feb, 2024
- 2 locations
A Study to Evaluate the Efficacy of Sage-217 in the Treatment of Adult Participants With Major Depressive Disorder (MDD)
The purpose of this study to evaluate the efficacy of SAGE-217 in the treatment of participants with MDD.
- 0 views
- 16 Feb, 2024
- 36 locations
Investigating the Effect of Single-session Sauna Use on Body Temperature
Whole-body hyperthermia (WBH) to an internal temperature of 38.5 C (101.3 F) using an infrared heating device has been associated with significant reductions in clinical depression. This prior work utilized a WBH medical device that is manufactured in Germany, is not FDA approved, and is not widely available.
- 0 views
- 16 Feb, 2024
- 1 location
ICBT for Mental Health Problems Related to the Coronavirus Pandemic
The study seeks to investigate the effects of a guided internet-based cognitive behavioral therapy (ICBT) programme a on adult mental health problems related to the current coronavirus pandemic. ICBT will be compared to a wait-list control group. Participants will be recruited in Sweden with a nationwide recruitment.
- 0 views
- 05 Aug, 2020
The Effects of Low Dose Ketamine on Cardiovascular Function
Low dose ketamine is used for pain management and for the treatment of anxiety and depression. Prior studies on low dose ketamine have noted short-term (minutes to hours) increases or decreases in blood pressure. Blood pressure that is too high or too low can be problematic if untreated.
- 0 views
- 16 Feb, 2024
- 1 location