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Found 66 clinical trials
Anesthesia and Cancer Study: Colon

This study investigates the influence of type of anesthesia on survival and recurrence rate in patients receiving colon cancer surgery. The participants will be allocated to either the TIVA group and the inhalation group.

anesthesia
propofol
sevoflurane
cancer
cancer surgery
  • 0 views
  • 16 Feb, 2024
  • 2 locations
A Clinical Trial of Pembrolizumab (MK-3475) Evaluating Predictive Biomarkers in Subjects With Advanced Solid Tumors (KEYNOTE 158)

In this study, participants with multiple types of advanced (unresectable and/or metastatic) solid tumors who have progressed on standard of care therapy will be treated with pembrolizumab (MK-3475).

  • 0 views
  • 20 Jul, 2022
  • 24 locations
Aspirin Use for Gastric Cancer Prevention in the Early Gastric Cancer Patients

This study aimed to investigate the effect of low-dose (100 mg) asprin on the prevention of gastric cancer in the early gastric cancer patients with negative H. pylori status who underwent endoscopic submucosal dissection.

early gastric cancer
cancer treatment
aspirin
cancer
gastric cancer
  • 0 views
  • 16 Feb, 2024
  • 9 locations
A Study of BLYG8824A in Participants With Locally Advanced or Metastatic Colorectal Cancer

This study will evaluate the safety, tolerability, and pharmacokinetics of BLYG8824A and will make a preliminary assessment of the anti-tumor activity of BLYG8824A in patients with locally advanced or metastatic colorectal cancer.

measurable disease
PCR test
EGFR
metastatic colorectal cancer
irinotecan
  • 0 views
  • 05 Aug, 2020
Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal Cancer

This phase III trial studies how well a telehealth self-management program works in improving survivorship care and outcomes in stage I-III non-small cell lung cancer or colorectal cancer survivors. Survivor self-management program focuses on coaching patients on follow-up care after cancer treatments. Participating in the program may improve knowledge and …

stage iia lung cancer ajcc v8
small cell lung cancer
stage ia1 lung cancer ajcc v8
stage i colorectal cancer ajcc v8
carcinoma
  • 4 views
  • 16 Feb, 2024
  • 1 location
Initial Attack on Latent Metastasis Using TAS-102 for ct DNA Identified Colorectal Cancer Patients After Curative Resection

This trial is a randomized, double-blind, multinational Phase III study to evaluate the efficacy and safety of preemptive treatment with FTD/TPI compared with administration of placebo as follow-up, which is the standard of care, in patients who underwent curative resection of colorectal cancer and then tested positive for ctDNA.

adenocarcinoma
colorectal adenocarcinoma
tas-102
ct scan
diarrhea
  • 0 views
  • 05 Aug, 2020
Impact of Acetazolamide in Reducing Referred Postoperative Pain

Robotic assisted laparoscopic prostatectomy (RALP) is the standard treatment for prostate cancer, due to the benefits of decreased blood loss and length of stay.The procedure involves removing a man's prostate using a minimally invasive robotic approach under the guidance of a surgeon. In order to gain sufficient access, carbon dioxide …

analgesia
prostate cancer
laparoscopic procedures
laparoscopy
cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
Neoadjuvant mFOLFOXIRI Plus Bevacizumab With Selective Radiotherapy in Patients With High-Risk Locally Advanced Rectal Cancer

The results of TRIBE showed that FOLFOXIRI plus bevacizumab yield a high objective response rate (ORR) (65%), early tumor shrinkage (ETS) (62.7%) and depth of response (DoR) (43.4%) in patients with metastatic colorectal cancer. The investigators were motivated to investigate this triplet-drugs chemotherpay plus bevacizumab both by the possibility of …

total mesorectal excision
incontinence
metastatic colorectal cancer
colon cancer
folfox regimen
  • 0 views
  • 16 Feb, 2024
  • 1 location
Durvalumab (MEDI4736) Plus Total Neoadjuvant Therapy (TNT) in Locally Advanced Rectal Cancer

The addition of durvalumab to total neoadjuvant therapy (TNT) in locally advanced rectal cancer may improve the pathological complete response rate. The induction platinum-based chemotherapy may increase the neoantigen formation together with the chemoradiotherapy period. Starting durvalumab during the first chemotherapy session and continuing during the 6-week period of chemoradiotherapy …

neuropathy
carcinoma
serum bilirubin
unstable angina
adenocarcinoma of rectum
  • 0 views
  • 16 Feb, 2024
  • 10 locations
Organ Preservation Program Using Short-Course Radiation & FOLFOXIRI in Rectal Cancer

The purpose of the research is to evaluate whether both chemotherapy and radiotherapy can lead to higher rates of clinical complete response leading to organ preservation in human subjects with cancer. The objective is to learn if this treatment approach may safely be used as an alternative to the standard …

total mesorectal excision
organ preservation
folfox regimen
adenocarcinoma of rectum
absolute neutrophil count
  • 0 views
  • 16 Feb, 2024
  • 1 location