car t-cell therapy Clinical Research Trials

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Found 13 clinical trials

Phase 1
For Seniors
For adults
Recruiting in 10s
Interventional Study
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Hematology
Recruiting

Assessment of Safety and Efficacy of IM19 for Recurrent or Refractory (R/R) Non-Hodgkin's Lymphoma(NHL) Patients

This is a phase I/II, multicenter study to assess the efficacy and safety of IM19 CAR-T cells in adult with R/R Non-Hodgkins Lymphoma in China.

hodgkin's disease

lymphoma

non-hodgkin lymphoma

targeted therapy

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16 Feb, 2024
1 location

Phase 1
For pediatric ages
For Seniors
Recruiting in 10s
Interventional Study
all
Family Medicine
Recruiting

Multi-CAR-T Cells Targeting B Cell Lymphomas

This study aims to evaluate safety and efficacy of a combination of 4th generation chimeric antigen receptor gene-modified T cells targeting B cell surface molecules including CD19 and alternative CARTs as booster and consolidation treatment for patients with highly resistant B cell lymphomas, including primary mediastinal B cell lymphoma (PMBCL) …

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16 Feb, 2024
3 locations

Phase 1
For Seniors
For adults
Recruiting in 10s
Interventional Study
all
Recruiting

Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MPP2+ Recurrent or Progressive Glioblastoma

This phase I trial studies the side effects and best dose of chimeric antigen receptor (CAR) T cells with a chlorotoxin tumor-targeting domain in treating patients with MPP2+ glioblastoma that has come back (recurrent) or that is growing, spreading, or getting worse (progressive). Vaccines made from a gene-modified virus may …

tumor cells

karnofsky performance status

expression by immunohistochemistry

mpp2

recurrent disease

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16 Feb, 2024
1 location