Found 18 clinical trials
Investigation of the Effects of Exercise on Patients With Chiari Malformation
Chiari Malformation (CM) is a posterior brain anomaly caused by the displacement of the brain stem and cerebellum into the cervical spinal canal. There are 8 types of Chiari malformations described today that vary according to the severity of the anomaly. In CM Type 1, cerebrospinal fluid (CSF) circulation deteriorated …
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- 16 Feb, 2024
- 1 location
Natural History and Clinical Features of Amyotrophic Lateral Sclerosis (ALS)
Describe the distribution of ALS in mainland China, to explore the differences in the number of ALS in different times, regions and populations in order to further explore the causes affecting the distribution of ALS; To investigate the cause of ALS in mainland China in the crowd disease development process …
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- 05 Aug, 2020
The Effect of Midazolam Sedation on Diagnostic Medial Branch Blocks
This prospective observational study aims to investigate the effect of midazolam sedation on the diagnostic validity of diagnostic lumbar medial branch block in patients diagnosed with lumbar spondylosis without myelopathy.
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- 05 Aug, 2020
The Pre-symptomatic Familial Amyotrophic Lateral Sclerosis (Pre-fALS) Study (Pre-fALS)
Pre-fALS is a prospective natural history and biomarker study of people not yet affected with ALS, but who are at genetic risk for developing ALS. The investigators aim to recruit unaffected (healthy) people from familial ALS (fALS) pedigrees in which a known genetic mutation associated with ALS has been identified; …
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- 01 Feb, 2024
- 1 location
Analysis of the Motion Activity Manual Wheelchair Users
Currently, there is no system in place to allow manual wheelchair users to know their quantities of movement activities and the intensity of effort to be provided during these propulsion movements. Based on recent work by Routhier et al. in 2017, and in light of the scientific literature related to …
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- 16 Feb, 2024
- 1 location
Descriptive Study of Acute Spontaneous Spinal Cord Infarction
Differential diagnosis with other transverse myelopathy causes is a common issue. As in cerebral stroke, there are multiple causes and mechanisms in spontaneous SCI, often difficult to clearly establish.
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- 16 Feb, 2024
- 1 location
Effectiveness of the Collaborative Community Clinic for Persons With Spinal Cord Injury and Disease
The investigator is evaluating data stored on the Collaborative Community Clinic data repository (IRB #201811032). Researchers seek to evaluate the effectiveness of the Collaborative Community Clinic (CCC), an occupational therapy student experiential learning clinic for uninsured or under-insured people with spinal cord injury and disease (SCI/D), using participants' initial and …
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- 05 Aug, 2020
Bone-biomarkers of Spinal Cord Injury Patients
Patients with spinal cord injury have a high prevalence of osteoporosis due to chronic skeletal unloading. Recently, various treatment drugs for osteoporosis have been developed. In particular, romosozumab, a sclerostin inhibitor, has been reported to have a high therapeutic effect as an inhibitor of bone resorption while promoting bone formation. …
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- 16 Feb, 2024
- 1 location
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