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Found 15 clinical trials
Systematic Assessment of SARS-CoV-2 Neurotropic Capacity in Modestly and Critically Ill Patients and Patients Who Died From COVID-19

This study is to analyze the microglia reaction or direct neurotropic effects of CNS COVID-19 in pathogenesis and brain stem dysfunction in critically ill patients. A microglia-focused, brain-specific 50+ marker CODEX panel is used to assess the neuroinflammatory microenvironment in specific brain regions of deceased COVID-19 patients. The peripheral (cerebrospinal …

  • 0 views
  • 16 Feb, 2024
  • 2 locations
Postoperative Neurocognitive Disorders

During this visit cognitive function will be assessed using the Wide Range Assessment of Memory and Learning (WRAML2) and Montreal Cognitive Assessment (MoCA) tests. Patients will also be asked to participate in a blood draw during the first 2 visits for fMRI (within five days of surgery and two days …

polysomnography
brain injury
delirium
confusion
neurocognitive disorders
  • 0 views
  • 16 Feb, 2024
  • 1 location
Evaluating the Role of Inflammation in Neonatal Epileptogenesis

The purpose of this study evaluate the relationship between inflammation and epilepsy in neonates with seizures after birth.

encephalopathy
epilepsy
acute brain injury
inflammatory response
seizure
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  • 16 Feb, 2024
  • 4 locations
AML/MDS Drug Sensitization by in Vivo Chemotherapy Administration

In this study, the investigators will explore the feasibility of ex vivo drug screening to predict sensitivity to chemotherapy resistance and to identify novel synergy between chemotherapies.

azacitidine
acute myeloid leukemia
myelodysplastic syndrome
aml/mds
myeloid leukemia
  • 0 views
  • 16 Feb, 2024
  • 1 location
The Role of MicroRNA in the Diagnosis Prognosis and Response to Treatment in Pancreatic Cancer

Aberrant miRNA production has been linked to a wide range of human cancers and shown to play important roles in their genesis and growth. These miRNA can be detected in the blood and tumors of patients with cancer. We hypothesize that the detection of certain miRNAs present in the blood/serum …

carcinoma
measurable disease
recurrent disease
adenocarcinoma
pancreatic cancer
  • 0 views
  • 05 Aug, 2020