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Found 25 clinical trials
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer ALCHEMIST Chemo-IO Study

This phase III ALCHEMIST trial compares the addition of pembrolizumab to usual chemotherapy versus usual chemotherapy for the treatment of stage IB, II, or IIIA non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the …

immunodeficiency
lung non-small cell squamous carcinoma
carcinoma
pemetrexed
sarcoma
  • 0 views
  • 16 Feb, 2024
  • 359 locations
The Efficacy of Adjuvant Chemotherapy in Locally Advanced Cervical Cancer

The aim of this trial was to evaluate the efficacy of adjuvant chemotherapy in the locally advanced cervical cancer with residual lesions after concurrent chemoradiation therapy.

paclitaxel
adenosquamous carcinoma
squamous cell carcinoma
cervical cancer stage
immunomodulator
  • 0 views
  • 05 Aug, 2020
Adjuvant Chemotherapy for Triple Negative Breast Cancer Patients With Residual Disease After Neoadjuvant Chemotherapy

This study will evaluate the efficacy and safety of antharcycline-based adjuvant chemotherapy compared with observation in triple negative breast cancer (TNBC) patients with residual invasive disease after platinum and taxanes based neoadjuvant chemotherapy.

tumor excision
residual tumor
triple negative breast cancer
adenocarcinoma
HER2
  • 0 views
  • 16 Feb, 2024
  • 1 location
Study of Tumor Infiltrating Lymphocytes Following CCRT in the Treatment of Patients With Cervical Carcinoma

A Phase II trial to study the effectiveness and security of cisplatin concurrent chemoradiotherapy plus TIL versus cisplatin concurrent chemoradiotherapy only in treating patients with FIGO stage IIIA to IVA cervical carcinoma.

adenosquamous carcinoma
squamous cell carcinoma
adenocarcinoma
cervical cancer
cisplatin
  • 0 views
  • 05 Aug, 2020
Assessing the Rate of Complications in X-Ray Therapy Versus Proton Beam Radiation Therapy After Breast Conserving Surgery or Mastectomy in Treating Patients With Breast Cancer

This phase II trial investigates the rate of complications of x-ray therapy versus proton beam radiation therapy after breast conserving surgery or mastectomy in treating patients with breast cancer. X-ray therapy is a form of radiation therapy that uses high-energy radiation from x-rays to kill tumor cells and shrink tumors. …

stage iiia breast cancer
prognostic stage iib breast cancer ajcc v8
stage iiic breast cancer
stage iib breast cancer
tumor cells
  • 0 views
  • 05 Jan, 2021
Concurrent Chemoradiation and Durvalumab for Locoregionally Advanced Nasopharyngeal Carcinoma

The investigators propose a phase II randomized-controlled study on using durvalumab in combination with induction chemotherapy followed by concurrent chemoradiation and adjuvant durvalumab, compared to induction chemotherapy followed by concurrent chemoradiation for previously untreated locoregionally advanced stage III to IVA NPC. In parallel, the investigators will also perform collateral tumor …

organ transplantation
corticosteroids
ffpe
formalin-fixed paraffin-embedded
pet/ct scan
  • 0 views
  • 05 Aug, 2020
Investigation of Genomic Alteration in Patients With Luminal A or Luminal B Subtypes

This is a translational study in patients with operated early breast cancer of Luminal A or Luminal B sub types.The Hellenic Cooperative Oncology Group (HeCOG) has designed an observational biomarker-driven study in patients with Luminal A or Luminal B breast cancer, with the aim to collect valuable biological material from …

luminal
luminal b breast cancer
luminal a breast cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
Quality of Life in Advanced Gastric Cancer Patients Receiving Neoadjuvant Chemotherapy

The purpose of this study is to explore the influence of neoadjuvant chemotherapy in the long term quality of life with advanced gastric cancer patients.

  • 0 views
  • 16 Feb, 2024
  • 1 location
Oxaliplatin Adjuvant Chemotherapy After Curative Resection of Primary Colon Cancer

According to general medical guidelines, adjuvant chemotherapy is used after curative resection of high-risk stage II or III primary colon cancer. However, there exist limitations using clinical trial data acquired from highly selected subjects in a controlled environment.

  • 0 views
  • 16 Feb, 2024
  • 1 location
BESPOKE Study of ctDNA Guided Therapy in Colorectal Cancer

Patients will receive SIGNATERA test results and may be recommended for adjuvant chemotherapy or observation by their treating clinician. Patients will be followed for up to two years with periodic whole blood collection.

adenocarcinoma of the colon
adenocarcinoma
adenocarcinoma of colon
cancer
formalin-fixed paraffin-embedded
  • 0 views
  • 16 Feb, 2024
  • 17 locations