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Found 142 clinical trials
Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Head and Neck Cancer

The objective of this study is to demonstrate the feasibility of novel MRI-guided ultrasound stimulated microbubble treatment to enhance radiation effects in humans receiving external beam radiotherapy delivered using a LINAC (linear accelerator) radiation therapy device.

carcinoma
squamous cell carcinoma
dental caries
head and neck cancer
external beam radiotherapy
  • 0 views
  • 05 Aug, 2020
Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Chest-wall and Locally-Advanced Breast Cancer

The objective of this study is to demonstrate the feasibility of novel MRI-guided ultrasound stimulated microbubble treatment to enhance radiation effects in humans receiving external beam radiotherapy delivered using a LINAC (linear accelerator) radiation therapy device.

carcinoma
breast cancer staging
potassium
advanced breast cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
PRAGMA (Prostate Radio Ablation Guided by Magnetic Resonance Imaging Acquisition) in Metastatic Prostate Cancer

Patients with metastatic prostate cancer can undergo MRI-guided prostate Stereotactic body radiation therapy (SBRT) without significant adverse events, similar to what has been reported for patients with localized prostate cancer.

adenocarcinoma of prostate
non-metastatic prostate cancer
adenocarcinoma
MRI
stereotactic body radiation therapy
  • 0 views
  • 16 Feb, 2024
  • 1 location
The Influence of a Perturbation Training on Balance Recovery of Old Adults: a Randomized Controlled Trial

We also hypothesize that brain function as seen in MRI will be improved in both training methods, more in the random training method. As far as we know, there is a lack of studies investigating the learning effect of random vs.

  • 0 views
  • 16 Feb, 2024
  • 3 locations
A Novel Multi-factorial Criteria-based Rehabilitation Program for Chronic Mid-portion Achilles Tendinopathy

The patients will be diagnosed by a sports medicine doctor and an MRI scan and will be experiencing palpable Achilles pain at the time of inclusion. The patients will be randomized into either a group performing the Silbernagel combined concentric-eccentric program, or a group performing a novel multi-phase program with …

tendinopathy
  • 0 views
  • 05 Aug, 2020
Treatment of Refractory Diamond-Blackfan Anemia With Eltrombopag

Eligibility People ages 2 and older with DBA who did not respond to steroids or could not take them, or their disease has returned despite taking them Design Participants will be screened with: Medical and medicine history Physical exam MRI: Participants will lie in a machine that takes pictures of …

blood cell count
cell counts
electrocardiogram
bone marrow erythroid
bone marrow biopsy
  • 0 views
  • 16 Feb, 2024
  • 1 location
Neoadjuvant Tucidinostat and Exemestane in Early Breast Cancer

This study is to evaluate the efficacy of tucidinostat combined with exemestane as neoadjuvant strategy in estrogen receptor-positive early breast cancer patients and explore the genetic model which can predict neoadjuvant endocrine therapeutic results.

estrogen receptor
exemestane
estrogen
invasive breast cancer
tucidinostat
  • 2 views
  • 05 Aug, 2020
MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment

In spinal cord tumors requiring surgical intervention, the resection difficulty is determined by two significant factors: tumor stiffness and adhesion to surrounding tissue. The stiffness of the tumor dictates the complexity of removal, while strong adhesion presents additional challenges during the surgical procedure. This clinical trial aims to assess the …

Accepts healthy volunteers
  • 0 views
  • 25 Jul, 2023
  • 22 locations
A Trial of Neoadjuvant mXELOXIRI Versus CRT in the EMVI Positive LARC

Extramural Vascular Invasion Positive(EMVI+) is a high risk of distant metastasis for locally advanced rectal cancer(LARC) after resection. The study is to evaluate the efficacy and safety of XELOXIRI as neoadjuvant chemotherapy alone for EMVI+ LARC in contrast to the efficacy of standard Chemoradiotherapy (CRT).

platelet count
renal function
adenocarcinoma
rectal carcinoma
chemoradiotherapy
  • 0 views
  • 05 Aug, 2020
Vertebral Body Sparing Craniospinal Irradiation for Pediatric Patients With Cancer of the Central Nervous System

This trial studies the feasibility of using intensity modulated proton therapy to deliver craniospinal irradiation while avoiding the bones of the vertebral column. Intensity modulated proton therapy is an advanced radiation therapy modality that uses high energy protons to kill cancer cells and shrink tumors, and may reduce the side …

  • 0 views
  • 16 Feb, 2024
  • 2 locations