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Found 1835 clinical trials
Study of Pexidartinib in Participants With Moderate Hepatic Impairment Compared With Healthy Participants

The pharmacokinetics of a single dose of pexidartinib will be investigated in participants with impaired hepatic function and compared with healthy control participants with normal hepatic function.

  • 0 views
  • 16 Feb, 2024
  • 2 locations
A Study of Copanlisib Combined With Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer

Treatment may also be stopped if the patient withdraws consent, or study termination occurs.

sipuleucel-t
palb2
CHEK1
metastatic disease
ejection fraction
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of MSB2311 in Advanced Solid Tumors

The maximum treatment duration is 2 years. During the study, subjects will be evaluated for safety and toxicity, PK/PD, immunogenicity and anti-tumor activity of MSB2311.

solid tumour
monoclonal antibodies
metastasis
  • 0 views
  • 16 Feb, 2024
  • 1 location
Acupuncture for Irritable Bowel Syndrome Patients

In this study, a 14-week, single blinded, randomized controlled clinical trial will be conducted to determine whether acupuncture could have significant benefits than sham acupuncture for IBS.

irritable bowel syndrome
acupuncture
  • 0 views
  • 16 Feb, 2024
  • 1 location
Flu-Bu-Mel Conditioning Regimen for Myeloid Disease

For patients with acute myeloid leukemia (AML) or myelodyspasia syndrome undergoing allo-HSCT, the conditioning regimen will be 5-day Fludarabine, 2-day Busulifan and 2-day melphalan

  • 0 views
  • 16 Feb, 2024
  • 2 locations
First In Human Study With ABBV-CLS-579 When Given Alone Or In Combination With Programmed Cell Death-1 Inhibitor In Participants With Locally Advanced Or Metastatic Tumors

In the combination therapy arm, escalating doses of ABBV-CLS-579 will be given in combination with a PD-1 inhibitor. Adult participants with a diagnosis of some solid tumors for which no effective standard therapy exists, or has failed will be enrolled.

  • 0 views
  • 05 Aug, 2020
Moxidectin for LF Cote d'Ivoire (DOLF)

The purpose of this study is to determine whether moxidectin (Mox) will be more effective than ivermectin (IVM) when used in single-dose combination therapies for lymphatic filariasis (LF).

combination therapy
moxidectin
antifilarial
filariasis
ivermectin
  • 0 views
  • 16 Feb, 2024
  • 1 location
New Intervention Protocol With Inspirometer Versus 2 Modalities of Pulmonary Intervention: INSPUL-REHAB

A clinical trial will be carried out in the area of physiotherapy and rehabilitation of the "Centro Integral de Rehabilitacin S.C. at the Hospital Angeles Lomas" in Mexico.

  • 0 views
  • 16 Feb, 2024
  • 1 location
Safety of Manganese Restriction in Neonatal Parenteral Nutrition

Participants will be <= 32 weeks gestational age (GA) neonates randomized to parenteral nutrition (PN) prepared with standard dose trace elements or to PN prepared with standard trace elements minus manganese.

  • 0 views
  • 16 Feb, 2024
  • 1 location
Dose Escalation Study of PF-07209326 in Healthy Participants

This Phase 1 first-in-human single ascending dose and multiple dose study will be a randomized, double-blind, placebo-controlled investigation of the safety, tolerability, and pharmacokinetics of PF-07209326.

  • 0 views
  • 16 Feb, 2024
  • 1 location