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Found 1862 clinical trials
Asthma: Phenotyping Exacerbations 2

The main outcomes of this study are to establish a cohort of well-phenotyped asthma patients with a recent history of an exacerbation. We aim to describe exacerbation profiles (phenotypes) of the cohort in terms of inflammatory/biomarker profile and bacterial/viral infection status and to compare these with exacerbation events in the …

corticosteroids
spirometry
prick skin
maintenance therapy
skin prick
  • 0 views
  • 16 Feb, 2024
  • 1 location
Asthma: Phenotyping EXacerbations

The main outcomes of this study are to establish a cohort of well-phenotyped asthma patients with a recent history of an exacerbation. We aim to describe exacerbation profiles (phenotypes) of the cohort in terms of inflammatory/biomarker profile and bacterial/viral infection status and to compare these with exacerbation events in the …

corticosteroids
spirometry
prick skin
maintenance therapy
skin prick
  • 0 views
  • 16 Feb, 2024
  • 1 location
Post-Neoadjuvant Treatment MRI Based AI System to Predict pCR for Rectal Cancer

In this study, investigators seek for a better way to identify the potential pathologic complete response (pCR) patients form non-pCR patients with locally advanced rectal cancer (LARC), based on their post-neoadjuvant treatment Magnetic Resonance Imaging (MRI) data. Previously, a post neoadjuvant treatment MRI based radiomics AI model had been constructed …

adenocarcinoma of rectum
adjuvant therapy
rectal cancer
chemoradiotherapy
metastasis
  • 0 views
  • 16 Feb, 2024
  • 3 locations
Standalone OMNI Surgical System for Open-angle Glaucoma

The emergence of minimally invasive glaucoma surgeries (MIGS) has seen a variety of potential innovative surgical alternatives to help better control intraocular pressure (IOP). The OMNI Surgical System (Sight Sciences, Menlo Park, CA, USA) is a promising MIGS procedure. It combines two procedures known as trabeculotomy and viscodilation of Schlemm's …

intraocular pressure
medical therapy
glaucoma
laser trabeculoplasty
ophthalmic surgery
  • 0 views
  • 16 Feb, 2024
  • 1 location
Characteristics and Outcomes of Patients With COVID-19 Admitted to the ICU

This is a case series of patients with COVID-19 admitted to the largest university hospital in Sao Paulo, Brazil, during the 2020 COVID-19 pandemic. Data will be collected prospectively and retrospectively. The main objective is to describe the characteristics of critically ill patients with COVID-19 and their clinical outcomes, and …

critical illness
critically ill
covid-19
  • 0 views
  • 01 Feb, 2023
  • 1 location
Effect of COVID-19 Pandemic on Perceived Stress Anxiety Mood and Training Quality in Elite Athletes.

In this study, we aim to investigate stress, anxiety, mood, life satisfaction measures among elite athletes during COVID-19 and explore the relationship between these measures and the changes in training characteristics in elite athletes during the COVID-19 pandemic.

anxiety
covid-19
  • 0 views
  • 05 Aug, 2020
Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

Background:Neurodegenerative disorders can lead to problems in movement or memory. Some can cause abnormal proteins to build up in brain cells. Researchers want to understand whether these diseases have related causes or risk factors.Objective:To test people with movement or thinking and memory problems to see if they are eligible for …

  • 0 views
  • 19 Feb, 2025
Radiomics-based Artificial Intelligence System to Predict Neoadjuvant Treatment Response in Rectal Cancer

In this study, investigators utilize a radiomics prediction model to predict the tumor response to neoadjuvant chemoradiotherapy (nCRT) before the nCRT is administered for patients with locally advanced rectal cancer (LARC). Previously, the radiomics prediction model has been constructed based on the radiomics features extracted from pretreatment Magnetic Resonance Imaging …

adenocarcinoma of rectum
adjuvant therapy
fluorouracil
rectal cancer
chemoradiotherapy
  • 0 views
  • 16 Feb, 2024
  • 3 locations
Effect of Mechanical Power on Dead Space Assessed by Volumetric Capnography: Preliminary Studies and Pilot Testing in ARDS Patients

This study assesses changes in physiological variables, aiming to determine whether a reduction in the mechanical power delivered by artificial ventilation while maintaining constant peep levels generates a reduction in the Bohrs dead space in patients with moderate to severe acute respiratory distress syndrome (ARDS). Commonly used ventilatory strategies aimed …

acute respiratory distress
mechanical ventilation
positive end expiratory pressure
  • 0 views
  • 16 Feb, 2024
  • 1 location
Evaluating the Role of Step Counts in Predicting Readmission and Mortality (STEP-CANCER)  

This study investigates the relationship between physical activity, heart rate, and sleep quality with recurrent hospitalizations among discharged oncology patients. Following discharge, patients will wear Huawei smartwatches to enable daily tracking of step count, heart rate, and sleep duration through a connected smartphone app. Patients will also complete the FACT …

  • 0 views
  • 14 Nov, 2024