Found 1835 clinical trials
A Study to Test Different Doses of BI 764532 in Patients With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for Delta-Like Ligand 3 (DLL3).
Phase Ib will further explore BI 764532 in selected patients populations based on data from phase Ia. The Phase Ib objectives, endpoints and design will be specified in a study protocol amendment after availability of phase Ia results.
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- 05 Aug, 2020
Pharmacokinetic Evaluation and Local Tolerability of Dry Powder Amikacin Via the Cyclops
To investigate local tolerability, lung function tests will be performed and the occurrence of adverse events will be scored.
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- 16 Feb, 2024
- 1 location
Cardiometabolic Effects of Rapid Glucose Excursion
The effects of rapid glucose excursions, induced by intravenous bolus application of glucose in healthy probands, on cardiometabolic and inflammatory parameters will be investigated
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- 05 Aug, 2020
Gait Re-education Program in Subjects With Parkinson´s Disease
The evaluators will be unaware of the patient's treatment status.
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- 04 Feb, 2022
- 1 location
Camrelizumab Combined With Apatinib Mesylate for Head and Neck Squamous Cell Carcinoma
This is a prospective, open-labelled study to evaluate the efficacy and safety of camrelizumab combined with apatinib mesylate in the induction treatment of patients with locally advanced head and neck squamous cell carcinoma who were judged surgically unresectable or appropriate for non-surgical definitive therapy. The objective response rate (ORR) and …
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- 16 Feb, 2024
- 1 location
Gene Therapy for Fanconi Anemia Complementation Group A
Hematopoietic stem cells from mobilized peripheral blood of patients with FA-A will be transduced ex vivo (outside the body) with a lentiviral vector carrying the FANCA gene. After transduction, the corrected stem cells will be infused intravenously back to the patient with the goal of preventing bone marrow failure.
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- 16 Feb, 2024
- 1 location
Safety Tolerability and Pharmacokinetics Study of Human Monoclonal Antibody BRII-198
This is a phase 1 study in which healthy adult volunteers will receive BRII-198 or placebo and will be assessed for safety, tolerability, and pharmacokinetics.
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- 16 Feb, 2024
- 1 location
Safety Tolerability and Pharmacokinetics Study of Human Monoclonal Antibody BRII-196
This is a phase 1 study in which healthy adult volunteers will receive BRII-196 or placebo and will be assessed for safety, tolerability, and pharmacokinetics.
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- 16 Feb, 2024
- 1 location
Tolerability Study of Panosyl Isomaltooligosaccharides (PIMO), in Subjects With Chronic Idiopathic Constipation (CIC)
The primary analysis will be conducted to assess the tolerability of MHS 1031 product and of the formulated placebo in randomized subjects with CIC diagnosed according to a modified Rome IV criteria.
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- 22 Nov, 2021
- 1 location
Low Dose Anti-inflammatory Radiotherapy for the Treatment of Pneumonia by COVID-19
Low radiation doses produce anti-inflammatory effects, which may be useful in the treatment of respiratory complications of COVID-19. This type of treatment is non-invasive and therefore, a priori, it can be used in all types of patients.
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- 16 Feb, 2024
- 3 locations