Found 1802 clinical trials
Cancer Therapy Effects on the Heart
Anthracycline chemotherapies (e.g. doxorubicin, daunorubicin) is commonly given to treat pediatric cancer, and carries a risk of cardiotoxicity. Over the long term, children who receive these therapies have an increased risk of heart failure and early cardiovascular death. However, current strategies for identifying patients who are at risk prior to …
- 0 views
- 16 Feb, 2024
- 1 location
B3 for NMD: Bench to Bedside and Back
Objective: The purpose of this study is to identify genetic or other markers in patient biosamples (e.g. blood, muscle, skin samples), electrodiagnostic studies or imaging that may help physicians and scientists provide faster ways to diagnose patients with NMD, study disease progression, and discover underlying disease mechanisms that may lead …
- 0 views
- 16 Feb, 2024
- 1 location
Longitudinal COVID-19 Cohort Study
Understanding these features of COVID-19 will improve the ability to design acute therapies and recovery-focused interventions. To address these knowledge gaps, the investigators propose a two-center, 225 patient longitudinal prospective cohort study of hospitalized COVID-19 patients with acute respiratory failure.
- 0 views
- 05 Aug, 2020
Highly Suppressive Treg in Delayed and Slow Graft Function After Kidney Transplantation
Ultimately, marginal kidney graft allocation could be directed to regulatory T cell-robust recipients and regulatory T cell-directed therapies could decrease marginal kidney graft discards without increasing delayed/slow graft function or impacting outcomes.
- 0 views
- 05 Aug, 2020
Natural History Study of Children and Adults With Adrenocortical Cancer (ACC)
They want to understand how adrenocortical cancer appear on imaging scans, how they respond to therapies, and the best treatment for them. Objective To gain a better understanding of adrenal cancer.
- 0 views
- 16 Feb, 2024
- 1 location
Cardiac Arrest Incidence and Outcome Among Patients With COVID-19 in French ICUs
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the novel coronavirus disease 2019 (COVID-19) pandemic. Among COVID-19 complications, in-hospital cardiac arrest (IHCA) was reported with a very poor outcome in a retrospective single-center study (0,7% of 30 days survival with good neurological outcome among IHCA patients with a …
- 0 views
- 16 Feb, 2024
- 41 locations
Evaluation of Eosinophil Phenotype in COPD Patients
This is a pilot non pharmacological observational study. Aim of the study is to analyze the immunophenotype of circulating eosinophils in chronic obstructive pulmonary disease (COPD) patients, and to correlate results with clinical status of patients (stable versus exacerbated patients, response to therapy). In about 30% of COPD patients there …
- 0 views
- 16 Feb, 2024
- 1 location
Evaluating the Role of Inflammation in Neonatal Epileptogenesis
The purpose of this study evaluate the relationship between inflammation and epilepsy in neonates with seizures after birth.
- 0 views
- 16 Feb, 2024
- 4 locations
Military Identity Project
The Military Identity Project is an exploration of military identity in Active Duty Service Members of the Army, Navy, Air Force & Marine Corps. The purpose of this project is to discover common identity attributes shared by active duty members across Service branches and to see if specific traits are …
- 0 views
- 16 Feb, 2024
- 1 location
Natural History Study of Children and Adults With Neuroendocrine Neoplasms (NEN)s
Background Neuroendocrine neoplasms (NENs) are rare tumors that originate in neuroendocrine cells. NENs can affect almost any part of the body. People with low-grade tumors can live many years. But high-grade tumors can be very aggressive. Researchers want to learn more about this type of cancer. This may help them …
- 0 views
- 05 Aug, 2020