Found 233 clinical trials
The CASCADE Study - Measures of Complement Activation and Inflammation in Patients With Covid-19
The investigators now need to know which of these complement chemicals are elevated in COVID-19 and compare to healthy volunteers, and assess whether the levels are higher in people with severe lung disease. The investigators believe that if levels are increased there are special treatments that can counteract them and …
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- 16 Feb, 2024
- 1 location
Correlation Between Specific Gene Mutationand Local Immune Microenvironment and Immunotherapy Efficacy in NSCLC
Immunotherapy for PD-L1 positive patients is still ineffective in some patientswhich may be related to the complex immune microenvironment.In view of this bottleneck, further refinement of immunotyping and in-depth study of drug resistance mechanism are the most important tasks. In this observational study, we evaluated the difference of gene mutation …
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- 16 Feb, 2024
- 1 location
Point of Care Ultrasound to Evaluate Diaphragmatic Function in Children Undergoing Thoracic Surgery
In addition, we examine if there is a relationship between diaphragmatic dysfunction and pulmonary complications, including postoperative lung atelectasis.
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- 05 Aug, 2020
Transgender Men Non-binary Persons and Testosterone Treatment BODY IDENTITY CLINIC
The study will focus on: Cardiovascular status and lung function Body composition Mental health and quality of life Establishing a biobank for later use.
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- 16 Feb, 2024
- 1 location
LAT for Oligoprogressive NSCLC Treated With First-line OSImertinib
To determine whether in patients with EGFR mutated advanced NSCLC and osimertinib as first-line treatment, the (repeated) use of LAT to 3 OP lesions and continuation of first-line osimertinib, improves the median progression-free survival by more than 3 months (i.e. PFS2-PFS1 = >3 months).
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- 16 Feb, 2024
- 1 location
Aflibercept or Bevacizumab as Second-line Treatment of RAS Mutated Metastatic Colorectal Cancer
Colorectal cancer is the third most frequent neoplasm after prostate and lung in man and breast and lung cancers in woman from Western Countries. The intensive study of predictive factors has strongly ameliorated the therapeutic flow-chart of metastatic colorectal cancer (mCRC) by allowing the selection of patients who benefit from …
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- 16 Feb, 2024
- 1 location
Comprehensive Digital Archive of Cancer Imaging-Radiation Oncology( CHAVI-RO )
In this phase, our study will include data sets of five types of cancers namely, breast, head and neck, brain, cervix and lung cancer. We propose to demonstrate the application of this data set in cancer research. We will work on serial PET-CT based radiomics of breast and cervix cancer …
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- 16 Feb, 2024
- 1 location
Quality of Life and Physical Performance After Novel Coronavirus Infection (COVID-19);
This study aims to observe the long-term health-related quality of life (HRQOL) and physical performance in individuals hospitalized due to a COVID-19 infection. Therefore, data is extracted from a study-site standard aftercare program which has been adjusted for this patient population. This comprehensive aftercare program includes education sessions and physical …
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- 05 Aug, 2020
Sputum Studies of Anti-Citrullinated Protein Antibodies (ACPA) and Rheumatoid Arthritis (RA) Origins
The study is designed to learn more about the causes of rheumatoid arthritis (RA). People who get RA have elevated protein markers called autoantibodies in their blood years before initial symptoms of arthritis. The goal of this study is to learn more about how autoantibodies in RA might be related …
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- 05 Aug, 2020
COVID-19: Respiratory and Sleep Follow-up
The current project is a prospective, multicentric cohort study aiming at a multidisciplinary assessment (pulmonary, cardiometabolic, sleep and mental health) of the consequences of infection by SARS-CoV-2, 3 months after the diagnosis in order to better characterize these complications. 400 patients with a positive diagnosis of SARS-CoV-2 will be included …
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- 16 Feb, 2024
- 4 locations