Found 1814 clinical trials
Pharmacokinetic Evaluation and Local Tolerability of Dry Powder Amikacin Via the Cyclops
To investigate local tolerability, lung function tests will be performed and the occurrence of adverse events will be scored.
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- 16 Feb, 2024
- 1 location
Cardiometabolic Effects of Rapid Glucose Excursion
The effects of rapid glucose excursions, induced by intravenous bolus application of glucose in healthy probands, on cardiometabolic and inflammatory parameters will be investigated
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- 05 Aug, 2020
Gene Therapy for Fanconi Anemia Complementation Group A
Hematopoietic stem cells from mobilized peripheral blood of patients with FA-A will be transduced ex vivo (outside the body) with a lentiviral vector carrying the FANCA gene. After transduction, the corrected stem cells will be infused intravenously back to the patient with the goal of preventing bone marrow failure.
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- 16 Feb, 2024
- 1 location
Gait Re-education Program in Subjects With Parkinson´s Disease
The evaluators will be unaware of the patient's treatment status.
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- 04 Feb, 2022
- 1 location
Camrelizumab Combined With Apatinib Mesylate for Head and Neck Squamous Cell Carcinoma
This is a prospective, open-labelled study to evaluate the efficacy and safety of camrelizumab combined with apatinib mesylate in the induction treatment of patients with locally advanced head and neck squamous cell carcinoma who were judged surgically unresectable or appropriate for non-surgical definitive therapy. The objective response rate (ORR) and …
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- 16 Feb, 2024
- 1 location
Safety Tolerability and Pharmacokinetics Study of Human Monoclonal Antibody BRII-198
This is a phase 1 study in which healthy adult volunteers will receive BRII-198 or placebo and will be assessed for safety, tolerability, and pharmacokinetics.
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- 16 Feb, 2024
- 1 location
Safety Tolerability and Pharmacokinetics Study of Human Monoclonal Antibody BRII-196
This is a phase 1 study in which healthy adult volunteers will receive BRII-196 or placebo and will be assessed for safety, tolerability, and pharmacokinetics.
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- 16 Feb, 2024
- 1 location
Study of Pexidartinib in Participants With Moderate Hepatic Impairment Compared With Healthy Participants
The pharmacokinetics of a single dose of pexidartinib will be investigated in participants with impaired hepatic function and compared with healthy control participants with normal hepatic function.
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- 16 Feb, 2024
- 2 locations
A Study of Copanlisib Combined With Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer
Treatment may also be stopped if the patient withdraws consent, or study termination occurs.
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- 16 Feb, 2024
- 1 location
A Study of MSB2311 in Advanced Solid Tumors
The maximum treatment duration is 2 years. During the study, subjects will be evaluated for safety and toxicity, PK/PD, immunogenicity and anti-tumor activity of MSB2311.
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- 16 Feb, 2024
- 1 location