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Found 1415 clinical trials
A Study of IBI377 in Combination With Corticosteroids for the Treatment of First-Line Acute Graft-Versus-Host Disease

The purpose of this study is to evaluate itacitinib in combination with corticosteroids as first-line treatment of participants with Grade II to IV acute graft-versus-host disease (aGVHD).

corticosteroids
graft versus host disease
hematologic malignancy
itacitinib
stem cell transplantation
  • 0 views
  • 16 Feb, 2024
  • 1 location
Clinical Trial to Evaluate the Efficacy of Food Supplement Manremyc Against SARS- COV-2 Infection (COVID-19) in Healthcare Workers

The purpose of this study is to assess the efficacy of Manremyc food supplement for reduce the incidence of SARS-CoV-2 infection in a high risk population, as healthcare workers.

acute respiratory syndrome (sars)
SARS
serologic test
  • 0 views
  • 16 Feb, 2024
  • 5 locations
Lenalidomide in Combination With R-GemOx in First-line Treatment of Elderly Diffuse Large B Cell Lymphoma

The purpose of this study is to investigate efficacy and safety of Lenalidomide in combination with R-GemOx as first-line treatment of elderly patients with Diffuse large B cell lymphoma.

lymphoma
diffuse large b-cell lymphoma
hiv related lymphoma
gemox
b-cell lymphoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
Clinical Study of Nab-paclitaxel Combined With Toripalimab in Local Advanced or Metastatic G/GEJ Carcinoma

This study is to evaluate the efficacy and safety of Albumin-bound paclitaxel combined with Toripalimab as first-line/second-line treatment of local advanced or metastatic gastric or gastroesophageal junction carcinoma.

  • 0 views
  • 05 Aug, 2020
A Study of Subcutaneous KY1005 in Healthy Volunteers

Single centre, open-label, single dose, parallel group study to investigate the PK, safety and tolerability of KY1005 after subcutaneous (s.c.) and intravenous (i.v.) administration, with i.v. KY1005 as a reference treatment.

  • 0 views
  • 16 Feb, 2024
  • 1 location
Intervetional Lay Open and Curettage Versus Endoscopic (E.P.Si.T) Method in the Treatment of Sacrococcygeal Pilonidal Sinus Disease

Aim of the work To compare lay open technique versus Endoscopic pilonidal sinus treatment as regards recurrence rate, operative data, postoperative pain, intra and postoperative complications, healing time and return to daily activity

  • 0 views
  • 05 Aug, 2020
JSI-1187-01 Monotherapy and in Combination With Dabrafenib for Advanced Solid Tumors With MAPK Pathway Mutations

This is a Phase 1 study of JSI-1187 as monotherapy and in combination with dabrafenib for the treatment of advanced solid tumors with MAPK pathway mutations, including mutations that cause MAPK pathway hyperactivation.

brain metastases
lung cancer
immunomodulators
solid neoplasm
metastasis
  • 0 views
  • 16 Feb, 2024
  • 4 locations
A Study to Evaluate the Efficacy and Safety of Sirukumab in Confirmed Severe or Critical Confirmed Coronavirus Disease (COVID)-19

The purpose of this study is to evaluate the clinical response of sirukumab (administered as a single intravenous dose) plus standard of care (SOC) compared to placebo plus SOC in COVID-19.

  • 0 views
  • 05 Aug, 2020
Neoadjuvant Tucidinostat and Exemestane in Early Breast Cancer

This study is to evaluate the efficacy of tucidinostat combined with exemestane as neoadjuvant strategy in estrogen receptor-positive early breast cancer patients and explore the genetic model which can predict neoadjuvant endocrine therapeutic results.

tucidinostat
invasive breast cancer
metastasis
cancer
estrogen
  • 2 views
  • 05 Aug, 2020
ExAblate Blood-Brain Barrier (BBB) Disruption for the Treatment of Alzheimer's Disease

The purpose of this study is to evaluate the safety and efficacy of the ExAblate Model 4000 Type 2.0 System as a tool to disrupt the blood-brain barrier (BBB) in patients with probable Alzheimer's Disease (AD).

alzheimer's disease
  • 0 views
  • 16 Feb, 2024
  • 3 locations