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Found 229 clinical trials
Safety and Tolerability of TOP-N53 Applied on Digital Ulcers in Patients With Systemic Sclerosis (TOP-N53-02)

Does TOP-N53 affect certain aspects of the illness like blood flow in the fingertip wounds, itch, pain, redness, bruises and bleeding at or beyond the fingertip wounds?Researchers will compare TOP-N53 solution in different strengths to a placebo (a look-alike substance that contains no drug) to see if TOP-N53 works to …

  • 0 views
  • 02 May, 2025
Investigation of the Effects of Exercise on Patients With Chiari Malformation

This study was planned to investigate the effects of two different exercise programs on pain, balance, coordination, proprioception, functional capacity, body posture, daily life activities and quality of life. The study was planned to involve at least 20 individuals with CM Type 1 who were not surgical indications in the …

  • 0 views
  • 16 Feb, 2024
  • 1 location
Neoadjuvant mFOLFOXIRI Plus Bevacizumab With Selective Radiotherapy in Patients With High-Risk Locally Advanced Rectal Cancer

Moreover, the short- and long-term adverse effects of radiotherapy such as chronic pain, faecal incontinence and urogenital/anal dysfunction are associated with poor quality of life. Neadajuvant chemotherpay (NACT) alone has been proposed instead of preoperative chemoradiotherapy (CRT) with the aim of elimination of potential micrometastasis as early as possible while …

MRI
fluorouracil
mfolfox-6
chemoradiotherapy
adjuvant
  • 0 views
  • 16 Feb, 2024
  • 1 location
Implementing a Guidelines-Based M-Health Intervention for High Risk Asthma Patients

            The goal of this research study is to test how good an app is in making asthma easier to manage for 372 adolescents/young adults. The app is a mobile version of the asthma action plan. mAAP

  • 8 views
  • 16 Feb, 2024
  • 1 location
Previously Implanted Pudendal Nerve Stimulation

This study seeks to examine the response of the bladder to different pudendal nerve stimulation frequencies, by studying patients who have been previously-implanted with pudendal nerve neurostimulators.

  • 0 views
  • 05 Aug, 2020
KUR-113 Bone Graft Versus Local Autograft for the Treatment of Single-level Transforaminal Lumbar Interbody Fusion

The purpose of this study is to evaluate the safety and efficacy of KUR-113 Bone Graft (TGplPTH1-34 in fibrin) compared to local autograft for the treatment of Degenerative Disk Disease (DDD).

leg pain
bed rest
scarring
osteophyte
spondylolisthesis
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Human Umbilical Cord Mesenchymal Stem Cells For the Treatment of Lumbar Disc Degeneration Disease

This study aims to investigate the safety and efficiency of Human Umbilical Cord Mesenchymal Stem Cells (hUCMSC) for treating lumbar disc degeneration diseases. We hypothesize grafting hUCMSC into the degenerative disc leads to symptoms relief and slow down the progression of disc degeneration.

lumbar disc degeneration
back pain
manipulative therapy
spinal surgery
morphine
  • 0 views
  • 16 Feb, 2024
  • 1 location
Effect of Low Level Laser Therapy After Wisdom Tooth Removal

The aim is to test the effect of low level laser therapy on the relief of symptoms after wisdom tooth removal.

low-level laser therapy
tooth extraction
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study to Compare Different Ways of Steroid Administration After Total Knee Implantation

We are going to evaluate the difference between perioperative intravenous steroid supplementation, perioperative periarticular steroid supplementation, and standard anaesthesia protocols. We'll evaluate the outcome of patients with knee osteoarthritis who are undergoing Total Knee Arthroplasty to understand which of the three treatments give more benefits to the patient.

osteoarthritis
anesthesia
dexamethasone
dexamethasone sodium phosphate
total knee replacement
  • 0 views
  • 16 Feb, 2024
  • 1 location
HidraWear AX HS Study

The product, HidraWear AX is and adhesive free wound dressing system for the every day home care of Hidradenitis Suppurativa (HS), a debilitating disease of the skin for which there are limited wound dressing products. This is a study to assess the use HidraWear Ax vs current product and method …

hidradenitis
  • 0 views
  • 05 Aug, 2020