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Found 1765 clinical trials
Innovative Trial for Understanding the Impact of Targeted Therapies in NF2

This is a multi-arm phase II platform-basket screening study designed to test multiple experimental therapies simultaneously in patients with neurofibromatosis type 2 (NF2) with associated progressive tumors of vestibular schwannomas (VS), non-vestibular schwannomas (non-VS), meningiomas, and ependymomas.

investigational therapy
ependymoma
cataract
neurofibroma
tubal ligation
  • 0 views
  • 05 Aug, 2020
Effectiveness of Kinesiotaping and Manipulation Therapies in Drooling Management Among Children With Oral Dysphagia

Children suffering from neurological problems may have a common problem of drooling and dysphagia.There is high prevelance of neurological disorders in developing countries including Pakistan.Parents of children with disability are highly stressed and burdenised while taking care of their children.there is a need to overcome the drooling and dysphagia problems …

  • 0 views
  • 16 Feb, 2024
  • 1 location
Food Supplements Based on Nettle and Peppermint to Control Signs and Symptoms Induced by Cancer Therapies

The main purpose of this study is to evaluate the impact of food supplements (herbal remedies) on sign and symptoms induced by cancer therapies: Nettle will be administered for improvement of anemia and fatigue; Peppermint will be administered for improvement of nausea.

fatigue
taxane
cancer
cyclophosphamide
inhibitors, parp
  • 0 views
  • 16 Feb, 2024
  • 1 location
Evaluation of GLR2007 for Advanced Solid Tumors

This study is designed to determine the safety, tolerability, and optimal dosing of GLR2007 in participants with advanced solid tumors that do not respond well to standard clinical therapies.

hair thinning
epidermal growth factor receptor
MRI
EGFR
immune checkpoint inhibitor
  • 0 views
  • 16 Feb, 2024
  • 4 locations
A Study Evaluating The Safety And Pharmacokinetics Of Escalating Doses Of RO7297089 In Patients With Relapsed Or Refractory Multiple Myeloma

This is a first-in-human Phase I, open-label, multicenter, global, dose-escalation study designed to evaluate the safety, tolerability, and pharmacokinetics of RO7297089 and make a preliminary assessment of anti-tumor activity in patients with R/R MM for whom no established therapy for MM is appropriate and available or who are intolerant to …

refractory multiple myeloma
measurable disease
multiple myeloma
  • 0 views
  • 05 Aug, 2020
CBM588 in Combination With Nivolumab and Cabozantinib for the Treatment of Advanced or Metastatic Kidney Cancer  

This phase I trial evaluates the effects of CBM588 in combination with standard therapies, nivolumab and cabozantinib, in treating patients with kidney cancer that has spread to other places in the body (advanced/metastatic).

  • 0 views
  • 14 Mar, 2022
  • 1 location
Ibrutinib + Venetoclax in Untreated WM

This research study involves an experimental drug combination of targeted therapies. The names of the study drugs involved in this study are: Venetoclax ibrutinib

myd88 gene mutation
platelet transfusion
serum pregnancy test
plasmapheresis
bone marrow biopsy
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Hyperpolarized Imaging for New Treatments

The introduction of triple combination CFTR modulator therapy for patients with Cystic Fibrosis (CF) with at least one copy of the deltaF508 mutation is expected to provide major health benefits, but will also require novel outcome measures that can detect CF lung disease at an early stage, capture the efficacy …

antibiotic therapy
antibiotics
cystic fibrosis transmembrane conductance regulator
pulmonary disease
pulmonary function test
  • 0 views
  • 16 Feb, 2024
  • 4 locations
Potassium-titanyl Phosphate (KTP) Laser vs KTP Laser and Ivermectin Cream for Facial Rosacea (KIR)

Treatments depend on the type and include topical and systemic antibiotics, azelaic acid, topical ivermectin, topical brimonidine, systemic isotretinoin as well as intense pulsed light (IPL) and laser therapies. For treatment of telangiectasia and redness, laser and IPL therapies are the first choice. Vascular lasers, such as pulsed dye lasers …

  • 0 views
  • 06 May, 2024
  • 2 locations
Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Alzheimer Disease

Impaired verbal communication is a cardinal symptom of Alzheimer Disease (AD) and the source of enormous distress and disability. Effective therapies for this deficit are lacking. In light of the emerging literature demonstrating that Transcranial Magnetic Stimulation (TMS) improves general cognition in subjects with Alzheimer Disease (AD), the investigators propose …

mini-mental state examination
cognitive impairment
alzheimer's disease
  • 0 views
  • 16 Feb, 2024
  • 1 location