Found 1692 clinical trials
Role of TTV During First-line Immunotherapy Treatment in Patients With Renal Cell Carcinoma (TTV ccRCC)
The aim of this project is to descriptively explore the trend of torquetenovirus viral load TTV during therapy with immune checkpoint inhibitor ICI in these patients, to evaluate a possible role of this virus as a biomarker of response.
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- 13 Jun, 2025
Trajectory of Microbiota Maturation in Healthy Bern Infants - a Network Approach
Methods: The investigators will recruit 120 pregnant mothers who will be followed as mother-baby pairs until 10 years of age. Infants will be followed clinically to determine adequate growth and development as well as pathology including abdominal pain.
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- 16 Feb, 2024
- 1 location
Retention and Durability of the Anterior Zirconia Wing Bridge
The type of zirconia-wing bridge the investigators are researching in this study has two wings which generally have three countersunk holes (meaning that the circumference of the outer portion of the hole is larger than the inner part of the hole). Composite resin (dental filling material) is placed in the …
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- 05 Aug, 2020
Effect of FFRCT-angio in Functional Diagnosis of Coronary Artery Stenosis
However, the stenosis severity is not closely corresponding with the hemodynamic significance in coronary arteries. As a result, fractional flow reserve (FFR) with pressure wire measurement was introduced to functionally assess the coronary stenosis.
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- 05 Aug, 2020
Immunotherapy in Lung Cancer: Treatment After IO Cessation.
Immunotherapy is now a standard of care for first-line and eventually salvage therapy in patients with stage IV NSCLC and as adjuvant after RT-CT for stage III NSCLC. The aim of the study is determining the therapeutic landscape and the reason for immunotherapy cessation.
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- 05 Aug, 2020
Serial Tumour Biopsies and Blood Biomarkers in Melanoma
It is hoped that soon we will be able to monitor cancer by analysing a patient's blood samples, thus reducing the need for biopsies. As blood tests could be taken more frequently, signs that patients are becoming resistant to treatments could be picked up sooner. As well as monitoring biomarkers, …
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- 16 Feb, 2024
- 1 location
On-line Neuromuscular Exercise and Education for Knee Osteoarthritis
Due to enforced social distancing as a direct consequence of the COVID-19 pandemic, many on-site health care services are unavailable. This study seeks to investigate the relative effectiveness of an alternative on-line delivery model of exercise and education compared to on-site delivery in patients with knee osteoarthritis.
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- 16 Feb, 2024
- 4 locations
New Time Clock for ST-elevation MI Based on Biochemical Myocardial Infarction Onset Time
It is essential to accurately determine the time of onset of myocardial infarction. Standard practice is to take the time of symptom onset as a surrogate for artery occlusion time. However symptom onset is a subjective parameter and affected by multiple factors such as recall issues in elderly patients and …
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- 05 Aug, 2020
Prevalence of Thiamine Deficiency in Hospitalized Non-Alcoholic Veterans
Thiamine micronutrient deficiency (TD) can cause a variety of non-specific symptoms and leads to several thiamine deficiency disorders such as heart failure, polyneuropathy, Wernicke's Encephalopathy and generalized weakness and debility. Symptoms are often vague and non-specific such as fatigue, leg swelling, imbalance, confusion, mood disorders, gastrointestinal upset, and weakness.
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- 17 Aug, 2022
- 1 location
Validity and Reliability of the Turkish Version of the Sydney Swallow Questionnaire
Purpose of the study is the validity and reliability of the Turkish version of the Sydney Swallow Questionnaire (SSQ-T), so that it would be used as an assessment tool for Turkish dysphagia patients. Despite being translated and validated in many languages, there is no validated Turkish version of SSQ to …
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- 16 Feb, 2024
- 1 location