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Found 1415 clinical trials
4SCAR-T Therapy Post CD19-targeted Immunotherapy

This study will evaluate safety and efficacy of a combination of 4th generation chimeric antigen receptor gene-modified T cells (4SCAR-T) targeting CD19-negative B-ALL that express alternative surface antigens such as CD22, CD10, CD20, CD38, and CD123, as many patients relapse after anti-CD19 immunotherapy. Clinical response and optiminzation of a standardized …

  • 0 views
  • 05 Aug, 2020
Low Dose Radiotherapy for COVID-19 Pneumonitis

Low dose radiotherapy (LD-RT) ( 100 cGy) induces an anti-inflammatory response, lowering levels of pro-inflammatory cytokines such as IL-1 or inhibit leukocyte recruitment. LD-RT has been used historically for the pneumonia treatment reporting a rapid clinical improvement (within the first week), as well as a reduced mortality (from around 30% …

acute respiratory syndrome (sars)
x-rays
pet/ct scan
pneumonia
inflammatory response
  • 0 views
  • 05 Aug, 2020
The Influence of a Perturbation Training on Balance Recovery of Old Adults: a Randomized Controlled Trial

We also hypothesize that brain function as seen in MRI will be improved in both training methods, more in the random training method. As far as we know, there is a lack of studies investigating the learning effect of random vs.

  • 0 views
  • 16 Feb, 2024
  • 3 locations
Study of Venetoclax in Combination With Azacytidine in AML Patients Selected Using Ex Vivo Drug Sensitivity Screening

The exploratory study will aim to find novel combinations for overcoming resistance as well as finding/validating biomarkers for both sensitivity and resistance.

refractory acute myeloid leukemia (aml)
neoadjuvant therapy
azacitidine
chronic stable angina
renal function
  • 0 views
  • 16 Feb, 2024
  • 1 location
Video-assisted Anal Fistula Treatment (VAAFT) Versus Fistula-tract Laser Closure (Filac) Versus Conventional Seton in the Management of Anal Fistula

Anal fistula is a chronic inflammatory tract connecting an internal opening in the anal canal with one or more than one external openings in the perianal skin Aim of the work This prospective randomized control trial, we will compare video-assisted anal fistula treatment (Vaaft) and Fistula Laser closure (Filac) and …

  • 0 views
  • 16 Feb, 2024
  • 1 location
Comparing the Consolidation Regimens of IDA With Intermediate-dose Cytarabine Versus Intermediate-dose Cytarabine Alone for Elderly AML Patients

This study evaluates Idarubicin (IDA) in combination with the intermediate-dose cytarabine, compared with intermediate-dose cytarabine alone, as a consolidation treatment for elderly AML in first remission.

anthracyclines
leukemia
arrhythmia
ejection fraction
heart failure
  • 0 views
  • 16 Feb, 2024
  • 1 location
Evaluation of Post Operative Pain in Retreatment of Molars Using Different Irrigant

This study evaluates the efficacy of dexamethasone as a intracanal irrigant along with sodium hypochlorite 1% and 5.25% concentrations in post treatment pain for molar root canal retreatment.

root canal
  • 0 views
  • 16 Feb, 2024
  • 1 location
Gated and Non-Gated Dynamic PET/CT Imaging

The goal of this study is to see how the images collected during the first hour compare with the routine images collected as part of the clinical scan.

  • 0 views
  • 16 Feb, 2024
  • 1 location
The Positively Quit Trial for Smoking Cessation

People in both groups will receive brief advice to quit and an offer of nicotine replacement therapy patches (NRT), as well as 12 videoconferencing group sessions. We will measure smoking behavior over a one year period and compare smoking rates for the treatment condition against AMC to see if the …

  • 0 views
  • 16 Feb, 2024
  • 1 location
Lung Irradiation for COVID-19 Pneumonia

The amount of radiation is much lower than what is typically used to treat other conditions such as cancer, although it is higher than the dose used for routine medical imaging.

remdesivir
coronavirus infection
aspirin
low dose radiation therapy
ritonavir
  • 0 views
  • 16 Feb, 2024
  • 1 location