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Found 180 clinical trials
TKR Rehabilitation Through the Immersive Virtual Reality in Aquatic Scenarios

This study is a multicenter non-randomized single-blind controlled trial, aimed at investigating the feasibility and efficacy of hydrotherapy based on IVR, for the patients with TKR, on the function, gait performance, postural balance control, and knee edema reduction.

epilepsy
drainage
total knee replacement
hydrotherapy
edema
  • 0 views
  • 16 Feb, 2024
  • 1 location
KEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated Nonsquamous NSCLC

This is a Phase 2, randomized, multicenter, double-blind study of the glutaminase inhibitor telaglenastat with standard-of-care pembrolizumab and chemotherapy versus placebo with standard-of-care pembrolizumab and chemotherapy for first line treatment of metastatic disease in patients with KEAP1/NRF2-mutated, stage IV, nonsquamous, non-small cell lung cancer (NSCLC).

metastasis
LKB1
adjuvant therapy
pembrolizumab
carboplatin
  • 0 views
  • 16 Feb, 2024
  • 28 locations
Cortico-Spinal tDCS as Rehabilitative Intervention in Amyotrophic Lateral Sclerosis

Transcranial direct current stimulation (tDCS) is a non-invasive technique, which has been demonstrated to modulate cerebral excitability in several neurodegenerative disorders and modulate intracortical connectivity measures. In this randomized, double-blind, sham-controlled study followed by an open-label phase, the investigators will evaluate whether a repetition of two-weeks' treatment with bilateral motor …

amyotrophic lateral sclerosis
excitability
primary lateral sclerosis
neurological disorder
neurodegenerative disorders
  • 0 views
  • 16 Feb, 2024
  • 1 location
Effect of HF rTMS on Serum BDNF in Cocaine Use Disorder

This study aims to explore the effect of 5-Hz rTMS over the left dorsolateral prefrontal cortex on the BDNF, craving and cognitive function. This study will be longitudinal, with a short-term double-blind placebo-controlled phase consisting of 20 rTMS sessions and a long-term phase, consisting of 2 weekly sessions for 12 …

  • 0 views
  • 03 Jan, 2024
  • 1 location
testslug trial title

Up to 25% of patients manifest a chronic course of illness, resulting in a need for additional treatment options. The DiSCoVeR trial is a multi-site, double-blind, sham-controlled, proof-of concept randomized controlled trial (RCT). The study aims to investigate the feasibility and efficacy of an innovative, combined treatment approach, incorporating transcranial …

  • 0 views
  • 09 Jul, 2021
Mobile App as a Guide to Exercises for Patients With Chronic Stroke

Objectives: To analyze adherence to physical rehabilitation by mobile App and to evaluate the effectiveness of lumbopelvic stability exercises performed at home with the App. Material and methods: Randomized controlled single blind pilot study (n = 30). Participants with Stroke (<6 months) will be randomized between two groups (App for …

hemiplegia
hemiplegia or hemiparesis
physical rehabilitation
hemiparesis
stroke
  • 0 views
  • 16 Feb, 2024
  • 1 location
Ginko Biloba Versus Desmopressin in Treatment of Children With Monosymptomatic Nocturnal Enuresis

Since Dimson in 1977 reported on the effects of desmopressinl" several double blind, placebo controlled studies have shown the efficacy of the drug often with rapid effect but also often with immediate relapse after ending treatment.

Accepts healthy volunteers
  • 0 views
  • 07 Apr, 2025
Does Insulin Sensitivity Impact the Potential of Metformin to Slow Aging

The investigators will use a dual-site, 12- week drug intervention trial performed in a double-blind, placebo-controlled manner on 148 subjects recruited from two separate sites (Oklahoma Medical Research Foundation (OMRF) and University of Illinois Urbana-Champaign (UIUC)).

insulin sensitivity
insulin resistance
metformin
muscle biopsy
chronic disease
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Implementation of an Early Rehabilitation Program for the Patient With Lung Transplantation: From the ICU to Home.

Objectives: To introduce an early rehabilitation program in the ICU after PT to see if there is an improvement in functionality, an increase in strength and muscle mass, an improvement in the strength of the respiratory muscles and a shorter hospitalization time in the ICU and in the ward. Methodology: …

treatment protocol
double lung transplantation
lung transplant
treatment protocols
pulmonary rehabilitation
  • 0 views
  • 16 Feb, 2024
  • 1 location
Virtual Reality Mobility Assessment of Functional Vision in Retinal Disease

Background The retina is a thin layer of tissue at the back of the eye. Retinal disease usually reduces a person s mobility because it affects how he or she moves through familiar and unfamiliar environments. Researchers want to see if a virtual reality (VR) tool can provide an easier …

  • 0 views
  • 16 Feb, 2024
  • 2 locations