Found 1415 clinical trials
The Effect and Mechanism of lncRNA NBR2 Regulating Endothelial Pyroptosis by Targeting GSDMD in Sepsis
Gasdermin D (GSDMD) mediated endothelial pyroptosis plays a critical role in modulating vascular endothelial injury in sepsis. Long non-coding RNA (lncRNA), as a class of non-coding protein RNA longer than 200 kD, contributes to a variety of cell biological processes. The dysregulation of lncRNA results in the occurrence and development …
- 0 views
- 05 Aug, 2020
A Multicenter Cross-sectional Study of Cardiac Ultrasound Phenotypes in Patients With Sepsis
The heart, one of the most important organs for oxygen supply and consumption, is frequently involved in sepsis, i.e. septic cardiomyopathy, also known as septic myocardial suppression. The occurrence of septic myocardial suppression increases mortality in septic patients. Recent studies have found that left ventricular hyperdynamic state (EF > 70%) …
- 0 views
- 14 Mar, 2022
Extra Vascular Lung Water and Pulmonary Permeability in Critically Ill Patients With SARS-CoV-2 (COVID-19)
In routine clinical practice, the investigators measure the EVLW and PVPI in ARDS patients, as suggested by expert's recommendations, using a transpulmonary thermodilution (TPTD) technique. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a newly recognized illness that has spread rapidly throughout Wuhan (Hubei province) to other provinces in China …
- 0 views
- 16 Feb, 2024
- 1 location
Cardiac Biomarkers in Preeclampsia: Prediction of Disease and the Risk of Future Cardiovascular Events in Survivors
Data Analysis: would be performed using the Statistical Package for Social Sciences (SPSS) software version 21.0. Numerical data would be expressed as mean standard deviation (SD). Results from the two groups of women would be compared using the independent T-test, Analysis of Variance (ANOVA) and the chi-square test while the …
- 0 views
- 16 Feb, 2024
- 1 location
Early Diagnosis of Upper Digestive Tract Disease
Exhaled breath testing is a non-invasive and acceptable technology utilising mass spectrometry (MS) which has shown promise at diagnosing cancer at an early stage. Previous research has shown that products formed as a result of metabolism can be measured in breath and saliva (biomarkers). This has the ability to accurately …
- 4 views
- 05 Aug, 2020
Evaluation of the Satisfaction of Patients Coming "on Foot" in the Operating Room
In this context, the optimization of the whole patient's journey during the perioperative period has been reviewed and adapted to personalized management within healthcare facilities. For more than a year now, multimodal approaches such as early rehabilitation have been undertaken, including morning admission with an innovative principle of "3D" patient …
- 0 views
- 05 Aug, 2020
Natural History Study of Children and Adults With Neuroendocrine Neoplasms (NEN)s
Participants home doctors will be contacted every 6 to 12 months. They will give medical data such as imaging and test results. Participants may have follow-up visits at NIH every 6 to 12 months. Participants will contact researchers if there are any changes in their tumor.
- 0 views
- 05 Aug, 2020
Clinical Study of Gastric Cancer Colorectal Cancer and Bladder Cancer Based on Liquid Biopsy
Endoscopy is the "gold standard"for the diagnosis of gastric cancer and colorectal cancer.gastric cancer and colorectal cancer treatment mainly includes surgery and medication.Compared with traditional diagnosis and treatment methods, the application of gene detection technology, especially high-throughput sequencing technology (NGS) in tumor diagnosis and treatment, performs multi-dimensional and multi-target detection …
- 2 views
- 05 Aug, 2020
Natural History Study of Children and Adults With Adrenocortical Cancer (ACC)
Participants home physician will be contacted every 6 to 12 months to collect medical information such as test results and scans. Participants may be asked to return to the NIH every 6 to 12 months for follow-up tests. Participants will contact study staff if there are any changes in their …
- 0 views
- 16 Feb, 2024
- 1 location
Effects of Lumbal Lordosis and Thoracic Kyphosis Angles on Muscle Activations During Different Low Back Exercises
In this approach, waist exercises and waist protection training are accepted as an effective and economical method. In our society, there is no conscious education and exercise habits about the techniques of protecting back health.
- 0 views
- 28 Feb, 2023
- 1 location