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Found 1346 clinical trials
Mechanism of Action of Transcranial Magnetic Stimulation

This is an observational neuroimaging study assessing the effects of TMS on the brains of patients with unipolar depression.

transcranial magnetic stimulation
depression
major depressive disorder
psychiatric care
psychiatric therapy
  • 0 views
  • 16 Feb, 2024
  • 1 location
Early Bactericidal Activity of Standard Drugs Used to Treat Mycobacterium Avium Complex: a Pilot Study

To assess the early bactericidal activity of Azithromycin 250mg by mouth daily over the first 14 days of treatment for Mycobacterium avium complex (MAC) lung disease.

azithromycin
lung disease
pulmonary disease
mycobacterial infections
mycobacterium avium complex infection
  • 0 views
  • 16 Feb, 2024
  • 1 location
First-in-Human Study of XMT-1592 in Patients With Ovarian Cancer and NSCLC Likely to Express NaPi2b

Phase 1b, a study in high grade serous ovarian cancer and nonsmall cell lung cancer to evaluate the safety and clinical activity of the antibody-drug conjugate (ADC) XMT-1592.

metastasis
hormonal contraception
ovarian cancer
lung cancer
cancer
  • 0 views
  • 16 Feb, 2024
  • 3 locations
Virtual Patient Behavioral Response Training for Family Caregivers

Our study is designed to help caregivers of someone with Alzheimer's Disease and related dementia to understand and deal with the difficult behaviors of a person with dementia.

dementia
alzheimer's disease
  • 0 views
  • 05 Aug, 2020
Changes in Brain Function Through Repeated Emotion Regulation Training

This is a pilot study that will investigate how two psychotherapies (re-interpretation and mindfulness) alter brain function. This information will be used to gain understanding of how repeated emotion regulation practices influence the brain and to develop a focused, tactic-based emotional regulation remediation approach for treatment of ADHD.

attention deficit hyperactivity disorder
depressive symptoms
depressed mood
psychotherapy
  • 0 views
  • 16 Feb, 2024
  • 1 location
Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Alzheimer Disease

Impaired verbal communication is a cardinal symptom of Alzheimer Disease (AD) and the source of enormous distress and disability. Effective therapies for this deficit are lacking. In light of the emerging literature demonstrating that Transcranial Magnetic Stimulation (TMS) improves general cognition in subjects with Alzheimer Disease (AD), the investigators propose …

cognitive impairment
mini-mental state examination
alzheimer's disease
  • 0 views
  • 16 Feb, 2024
  • 1 location
Long-term Consumption of Resistant Starch Type-4 (RS4)

The primary objective of the current proposal is to determine the effectiveness of long-term consumption of Fibersym RW for improving blood lipids (including cholesterol) and body composition. The overall goal of this clinical research is to determine the potential effects that RS4 consumption may have on the prevention of obesity …

cholesterol measurement
blood lipids
LDL Cholesterol
  • 0 views
  • 16 Feb, 2024
  • 1 location
The Effect of Time-Restricted Eating in Cardiometabolic Health

Time-restricted eating (TRE) is a dietary manipulation that involves restricting food intake to 6-12 h/day with no energy intake the rest of the day. In rodents, TRE improves metabolic function without caloric restriction, potentially by activating nutrient sensing mechanisms and effects on circadian oscillations. However, an understanding of the effect …

body mass index
insulin
hemoglobin a1c
insulin sensitivity
fasting
  • 0 views
  • 05 Aug, 2020
SPRINT Peripheral Nerve Stimulation for the Treatment of Back Pain

The purpose of this study is to compare standard of care treatments for back pain to electrical stimulation. Electrical stimulation is delivering small amounts of electricity to the nerves in your low back. This study will use a device called the SPRINT Peripheral Nerve Stimulation (PNS) System. The SPRINT PNS …

peripheral nerve stimulation
back pain
chronic pain
low back pain
electrical stimulation
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Suicide Prevention for Patients With Chronic Pain

Patients with chronic pain and moderate suicide risk (n=60) will be randomized to receive remote-PST or remote-supportive psychotherapy. We will assess problem-solving deficits through self-report, objective neuropsychological assessment and caregiver report. We have used an adaptive design so that if there is strong evidence for target engagement, we will continue …

suicidal
amplified musculoskeletal pain syndrome
chronic widespread pain
chronic pain
psychotherapy
  • 0 views
  • 16 Feb, 2024
  • 1 location