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Found 285 clinical trials
Irreversible Electroporation of Unresectable Liver Tumors

The aim of this study is to evaluate the safety and feasibility of curative intended irreversible electroporation (IRE) in the treatment of liver tumors neighboring major vessels or bile ducts.

hepatoma
cancer
metastasis
biliary tract cancer
irreversible electroporation
  • 0 views
  • 05 Aug, 2020
Changes in Brain Function Through Repeated Emotion Regulation Training

This is a pilot study that will investigate how two psychotherapies (re-interpretation and mindfulness) alter brain function. This information will be used to gain understanding of how repeated emotion regulation practices influence the brain and to develop a focused, tactic-based emotional regulation remediation approach for treatment of ADHD.

psychotherapy
depressive symptoms
attention deficit hyperactivity disorder
depressed mood
  • 0 views
  • 16 Feb, 2024
  • 1 location
Short Structured Psychological Intervention for Adults With ADHD - a Randomized Controlled Trial

The purpose of this study is to evaluate the effects of a novel psychological intervention for adult ADHD through a randomized controlled trial. Participants will be randomized to receive either a face-to-face manualized short psychological intervention, SAINT, or corresponding self-help material with limited access to therapist support. The main objective …

stimulant
substance use
psychiatric symptoms
attention deficit hyperactivity disorder
cns stimulants
  • 0 views
  • 05 Aug, 2020
Separation Surgery Followed by Stereotactic Ablative Body Radiotherapy (SABR) Versus SABR Alone for Spinal Metastases1234567 (SABR-MESCC)

This is a non-inferiority, randomised controlled trial to investigate the effect of stereotactic ablative body radiotherapy (SABR) compared to separation surgery followed by SABR in ambulatory patients with malignant epidural spinal cord compression (MESCC).The primary objective of the project is investigating the effect of SABR compared to separation surgery followed …

  • 0 views
  • 26 Sep, 2024
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU) (DIAN-TU)

To assess the safety, tolerability, biomarker, cognitive, and clinical efficacy of investigational products in participants with an Alzheimer's disease-causing mutation by determining if treatment with the study drug improves disease-related biomarkers and slows the rate of progression of cognitive or clinical impairment.

  • 0 views
  • 24 Feb, 2025
Isoleucine Intake and Intermediary Metabolism in Type 2 Diabetes

The primary objective of this study is to determine the mechanism of reduced branched-chain amino acid (BCAA) oxidation to propionyl CoA and isoleucine intake can affect TCA cycle function in obese insulin resistant T2D. We will test the hypotheses that isoleucine and valine oxidation to propionyl CoA is reduced and …

body mass index
  • 0 views
  • 16 Feb, 2024
  • 1 location
Development and Validation of the Client Centered Occupational Therapy Service Model

The purpose of the study is to develop and validate Client-centered Occupational Therapy Service at Taipei City Psychiatric Center (OT@tcpc) service model to assist clinicians to provide and integrate comprehensive OT services.

  • 0 views
  • 05 Aug, 2020
The Effectiveness of Telerehabilitation-Based Physiotherapy in COVID 19 Patients

Problems such as breathlessness, exercise intolerance and loss of peripheral muscle strength can be observed in individuals who have been diagnosed with COVID19 and have been discharged. In our study, it was aimed to investigate the effect of telerehabilitation physical therapy intervention to these cases by using videoconferencing method on …

breathlessness
therapy intervention
dyspnea
  • 0 views
  • 05 Aug, 2020
Effect of Standard Nutrition Therapy on Nutritional Status and Prognosis in Locoregionally Advanced Nasopharyngeal Carcinoma Patients With Malnutrition

This is a multicenter, randomized controlled, phase III clinical trial. The purpose of this study is to evaluate the efficacy of standard nutrition treatment versus conventional nutrition treatment in local advanced nasopharyngeal carcinoma patients.

nasopharyngeal carcinoma
karnofsky performance status
digestive system disease
malnutrition
nutritional support
  • 0 views
  • 05 Aug, 2020
The Effect and Safety of Low-level Laser Therapy in Acute Decompensated Heart Failure Patients.

The advantages of laser acupuncture are a non-invasive, painless, low risk of infection and high safety. Laser acupuncture as a treatment tool has the following advantages1.Painless, 2. Non-invasive treatment, the subject is highly accepted, the risk of infection and needle stick is low, 3. Very few side effects such as …

needle stick
edema
cardiogenic pulmonary edema
laser therapy
b-type natriuretic peptide
  • 0 views
  • 05 Aug, 2020