stem cell transplant Clinical Research Trials

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Found 1231 clinical trials

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Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Young Adults

The purpose of the CliniMACS TCR-Biotin System and CliniMACS CD19 is to improve the safety and efficacy of allogeneic HLA-partially matched related or unrelated donors HSCT when no matched donors are available, to treat malignant and nonmalignant disorders for which HSCT is the recommended best available therapy. Initially this device …

graft versus host disease

alt/ast

direct bilirubin

cardiovascular disease

hla-drb1

0 views
16 Feb, 2024
1 location

Phase 2
For pediatric ages
Recruiting in 100s
Interventional Study
all
Recruiting

Co-transplantation of MSC in the Setting of Allo-HSCT

Mesenchymal stem cells (MSCs) are known to exhibit immunomodulatory, anti-inflammatory, and pro-angiogenic properties, and therefore have the potential to improve the outcome of allogeneic hematopoietic stem cell transplantation (allo-HSCT) .The study is aimed to identify and evaluate the potential benefits of MSCs infusion during allogeneic HSCT, with regard to the …

graft versus host disease

cell transplantation

ejection fraction

0 views
16 Feb, 2024
1 location

Phase 2
For pediatric ages
Recruiting in 10s
Interventional Study
all
Recruiting

Low-dose AZA Combined With Short Term CAG Derived Regimen as a Bridging Treatment in Patients With Advanced MDS Prior to Allo-HSCT

This single arm, prospective study on the feasibility of a bridging treatment with low-dose azacitidine (AZA) in combination with short term CAG derived regimen prior to allogeneic stem cell transplantation (allo-HSCT) in patients with advanced myelodysplastic syndromes (MDS) .

allogeneic hematopoietic stem cell transplant

myelodysplastic syndrome

stem cell transplantation

myelodysplastic syndromes

azacitidine

0 views
16 Feb, 2024
1 location