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Found 1208 clinical trials
Efficacy and Safety of Sacubitril/Valsartan in Maintenance Hemodialysis Patients With Heart Failure

Cardiovascular disease (CVD) is the most common cause of death in end stage renal disease (ESRD) patients undergoing hemodialysis (HD). Hence, treatments to improve mortality and specifically cardiovascular outcomes in this population are greatly needed.

chronic disease
ejection fraction
nephropathy
angiotensin converting enzyme
angiotensin
  • 0 views
  • 05 Aug, 2020
Hyperpolarized 13C Pyruvate MRI Scan in Predicting Tumor Aggressiveness in Patients With Localized Renal Tumor

This feasibility study will evaluate how well hyperpolarized 13C pyruvate magnetic resonance imaging (MRI) scan works in predicting tumor aggressiveness in patients with localized renal tumor. Hyperpolarized 13C pyruvate is a non-radioactive substance with potential usage in the diagnostic imaging of tumors. Hyperpolarized 13C pyruvate MRI may help doctors determine …

MRI
renal neoplasm
aggressiveness
cancer
nephrectomy
  • 0 views
  • 16 Feb, 2024
  • 1 location
Lenvatinib and Pembrolizumab Before Surgery for the Treatment of Locally Advanced Non-Metastatic Kidney Cancer

This phase II trial studies how well lenvatinib and pembrolizumab before surgery work in treating patients with kidney cancer that has spread from its original site of growth to nearby tissues or lymph nodes but has not spread to other places in the body (non-metastatic). Lenvatinib may stop the growth …

tumor cells
primary tumor
international normalized ratio
beta human chorionic gonadotrophin
erythropoietin
  • 8 views
  • 05 Aug, 2020
  • 1 location
FAPI Imaging Predicts Adverse Cardiac Events in Chronic Total Occlusion (FACT-2)

Inclusion CriteriaAge ≥ 18 yearsPresence of at least one untreated chronic total occlusion (CTO) lesion in a major coronary artery (diameter ≥ 2.5 mm, TIMI 0 flow for ≥ 3 months) confirmed by coronary angiography or CTCAPatient eligible for PCI and undergoing FAPI PET/CT imaging prior to interventionWritten informed consent …

  • 0 views
  • 16 Jun, 2025
Breath Stacking Technique Associated With Expiratory Muscle Training in Amyotrophic Lateral Sclerosis Patients

it will be conducted a randomized parallel controlled trial with patients diagnosed with Amyotrophic Lateral Sclerosis (ALS) to compare two techniques to lung recruitment and cough augmentation, to assess their effects on pulmonary function, global functionally, swallowing and ability to speech in these population.

neuromuscular diseases
respiratory disease
mechanical ventilation
primary lateral sclerosis
cough
  • 0 views
  • 16 Feb, 2024
  • 1 location
Global Kidney Patient Trials Network

This is a prospective international multi-centre, observational cohort study of incident and prevalent patients diagnosed with a kidney disease

nephropathy
  • 0 views
  • 16 Feb, 2024
  • 1 location
Leptospirosis Registry Gathers Knowledge on Epidemiology Clinical Course Prognostic Factors and Molecular Characteristics for Invasive Leptospirosis Disease

Leptospirosis is a worldwide zoonotic diseases caused by pathogenic Leptospira spp. Human are accidental hosts, who acquired infections after exposition to animal urine, contaminated water or soil, infected tissue. Incidence of invasive leptospirosis disease causing acute kidney injury, acute respiratory distress syndrome (ARDS), myocarditis, hepatic dysfunction, hemorrhage and multi-organ failure, …

  • 0 views
  • 16 Feb, 2024
  • 1 location
Psychiatric Disturbances and COVID-19 Infection

This observational study aims at Assessment of the prevalence and types Psychiatric disturbances that affects patients with COVID-19 infection with and without previous psychiatric diseases. in addition to, Assessment of the types of Psychiatric disturbances in patients with COVID-19 infection in correlation to age, disease severity, co-morbid conditions and treatments …

psychiatric disturbances
covid-19
mental illness
  • 0 views
  • 16 Feb, 2024
  • 3 locations
Shear Wave Elastography in Differentiating Acute or Chronic Kidney Disease

Recent researches of shear wave elastography in evaluating renal parenchymal stiffness showed some correlation with nephropathy. In our study, aiming to facilitating clinical implication, the investigators will use swear-wave elastography combined with conventional renal sonography to benefit patients in diagnosis of acute or chronic kidney disease.

kidney function test
chronic disease
early diagnosis
nephropathy
dialysis
  • 0 views
  • 16 Feb, 2024
  • 1 location
Pediatric KIDney Stone (PKIDS) Care Improvement Network

The goals of this study are to improve the ability of pediatric patients and their caregivers to select surgical treatment options for kidney stones and to enable urologists to use techniques that result in the best outcomes for these surgeries.

lithotripsy
nephrolithotomy
shock
pediatric
ureterolithiasis
  • 0 views
  • 16 Feb, 2024
  • 22 locations