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Found 233 clinical trials
Cysteamine for Asthma

The purpose of this study is to see if a medicine called Cysteamine, given along with standard asthma care, will improve asthma symptoms and lung function.

eosinophil count
skin prick
corticosteroids
pulmonary function test
skin prick test
  • 14 views
  • 16 Feb, 2024
  • 1 location
First-in-Human Study of XMT-1592 in Patients With Ovarian Cancer and NSCLC Likely to Express NaPi2b

Phase 1b, a study in high grade serous ovarian cancer and nonsmall cell lung cancer to evaluate the safety and clinical activity of the antibody-drug conjugate (ADC) XMT-1592.

ovarian cancer
primary peritoneal carcinoma
alopecia
fallopian tube
peritoneal cancer
  • 0 views
  • 16 Feb, 2024
  • 3 locations
Inhaled Ibuprofen to Treat COVID-19

The study aims to evaluate the reduction in severity and progression of lung injury with inhaled ibuprofen in patients with severe acute respiratory syndrome due to SARS-CoV-2 virus.

diabetes
covid-19
COPD
pulmonary disease
chronic obstructive pulmonary disease
  • 0 views
  • 05 Aug, 2020
Investigation of an Abdominal Compression Device

This study is applicable to patients undergoing lower lung or abdomen stereotactic ablative body radiotherapy (SABR) treatment. The purpose of the ACE 01 study is to identify if, the volume of healthy tissue within the treatment area and therefore subsequent side effects, can be reduced by using a commercially available …

primary cancer
primary malignant neoplasm
stereotactic body radiation therapy
epinephrine
lung cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression

Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. It is the most common form of lung cancer, accounting for around 85% of lung cancers.

erbb1
epidermal growth factor receptor
non-small cell lung cancer
cancer
EGFR
  • 0 views
  • 16 Feb, 2024
  • 39 locations
TD-0903 for ALI Associated With COVID-19

This Phase 2 study will evaluate the efficacy, safety, pharmacodynamics and pharmacokinetics of inhaled TD-0903 compared with a matching placebo in combination with standard of care (SOC) in hospitalized patients with confirmed COVID-19 associated acute lung injury and impaired oxygenation.

  • 0 views
  • 05 Aug, 2020
Breath Stacking Technique Associated With Expiratory Muscle Training in Amyotrophic Lateral Sclerosis Patients

it will be conducted a randomized parallel controlled trial with patients diagnosed with Amyotrophic Lateral Sclerosis (ALS) to compare two techniques to lung recruitment and cough augmentation, to assess their effects on pulmonary function, global functionally, swallowing and ability to speech in these population.

mini-mental state examination
amyotrophic lateral sclerosis
primary lateral sclerosis
respiratory disease
mechanical ventilation
  • 0 views
  • 16 Feb, 2024
  • 1 location
Durvalumab(MEDI4736) After chemoRadioTherapy(DART) for NSCLC-a Translational and Biomarker Study

The main aim is to identify and describe biomarkers in different sample types related to chemoradiation followed by durvalumab treatment for stage III PD-L1 negative and positive non-small cell lung cancer (NSCLC) patients' eligible for curatively intended chemoradiation. The hypothesis is that clinical differences in course of disease reflect underlying …

pet/ct scan
chemoradiotherapy
bilateral oophorectomy
non-small cell lung cancer
durvalumab
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Evaluation of GLR2007 for Advanced Solid Tumors

This study is designed to determine the safety, tolerability, and optimal dosing of GLR2007 in participants with advanced solid tumors that do not respond well to standard clinical therapies.

BRAF
sarcoma
cancer treatment
epidermal growth factor receptor
cancer
  • 0 views
  • 16 Feb, 2024
  • 4 locations
sdsc

cew

  • 0 views
  • 30 Mar, 2021
  • 1 location