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Found 11241 clinical trials
Clinical Trial to Evaluate the Efficacy and Safety of an Immunomodulatory Therapy for the Treatment of Patients With Moderate to Severe COVID-19 Infection

An Open-label, prospective, randomized, comparative, multiple doses applied in addition to the standard of care treatment of patients with moderate to severe COVID-19 infection

cough
pneumonia
dyspnea
fever
covid-19
  • 0 views
  • 05 Aug, 2020
Mobile Devices to Detect Early Pneumonitis in Stage III NSCLC Patients on Durvalumab.

A study of whether mobile devices can improve the detection of pulmonary AEs (including pneumonitis) in stage III NSCLC patients post-CRT, while on durvalumab.

  • 0 views
  • 05 Aug, 2020
Titration of Oxygen Levels During Mechanical Ventilation With Electronic Alerts

Fractional oxygen during mechanical ventilation, is a life sustaining therapy in the intensive care unit , used for about a million patients annually. Oxygen therapy needs to be tightly balanced as both hypoxia and hyperoxia are harmful. Establishing precision in oxygenation has significant implications for improving patient outcomes, resource utilization …

critical illness
mechanical ventilation
hypoxia
hyperoxia
alert
  • 0 views
  • 05 Aug, 2020
Waking Hypnosis in the Treatment of MS-related Fatigue

The proposed study is a single-center, single-blind three-group randomized (1:1:1) controlled trial (RCT) comparing two hypnosis interventions to waitlist control efficacy for MS-related fatigue.

fatigue
  • 0 views
  • 05 Aug, 2020
Neoadjuvant RCT Versus CT for Patients With Locally Advanced Potentially Resectable Adenocarcinoma of the GEJ

This is a multicenter, prospective, randomized, stratified, controlled, open-label study comparing neoadjuvant radiochemotherapy with FLOT versus FLOT chemotherapy alone fr patients with locally advanced, potentially resectable adenocarcinoma of the gastroesophageal junction (GEJ)

fluorouracil
estrogen
calcium
leucovorin
docetaxel
  • 0 views
  • 05 Aug, 2020
Baricitinib Placebo and Antiviral Therapy for the Treatment of Patients With Moderate and Severe COVID-19

This phase II trial studies the effect of baricitinib in combination with antiviral therapy for the treatment of patients with moderate or severe coronavirus disease-2019 (COVID-19). Treatment with antiviral medications such as hydroxychloroquine, lopinavir/ritonavir, and/or remdesivir may act against infection caused by the virus responsible for COVID-19. Baricitinib may reduce …

hypertension
pneumonia
cough
acute respiratory syndrome (sars)
PCR test
  • 0 views
  • 05 Aug, 2020
Effects of Lithium Therapy on Blood-based Therapeutic Targets in Parkinson's Disease.

This study aims to determine if one of three low doses of lithium therapy for 6 months can engage one or more blood-based therapeutic targets implicated in Parkinson's disease (PD) pathophysiology. Results of this study will help to determine if lithium therapy is worthwhile to further investigate as a potential …

antidepressants
nilotinib
brain stimulation
delusions
hallucinations
  • 0 views
  • 16 Feb, 2024
  • 1 location
The Value of Palliative Primary Tumor Resection in Metastatic Colon Cancer

The aim of this trial is to evaluate the value of palliative primary tumor resection in colon cancer patients with initially unresectable metastases and a positive response to induction chemotherapy which depends on gene testing.

metastatic colon cancer
metastasis
xelox
stage iv colon cancer
mfolfox6
  • 0 views
  • 05 Aug, 2020
Anesthesia and Cancer Study: Colon

This study investigates the influence of type of anesthesia on survival and recurrence rate in patients receiving colon cancer surgery. The participants will be allocated to either the TIVA group and the inhalation group.

colon cancer
sevoflurane
cancer surgery
propofol
cancer
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Role of Lymphnode Dissection in Men With Prostate Cancer Treated With Radical Prostatectomy

This is particularly of interest considering the rapidly advancing technical possibilities, both in imaging and in the treatment of prostate cancer, since this enables an earlier and more individual intervention in the case of recurrence.

metastasis
immunological adjuvant
adjuvant
lymphadenectomy
prostatectomy
  • 0 views
  • 16 Feb, 2024
  • 1 location