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Found 1433 clinical trials
COMMIT HIV Trial Nepal

Community Healthcare Workers (CHWs), who live in the communities they serve, have the potential to reach patients who poorly engage in their care. Motivational Interviewing (MI) is a special type of interactional approach that focuses on improving the person's motivation to engage in healthy behaviors, such as keeping their clinic …

motivational interviewing
antiretroviral agents
hiv diagnosis
  • 0 views
  • 05 Aug, 2020
Thoracic Interfascial Plane Block Versus Thoracic Paravertebral Block in Gynecomastia Surgery

The growing increase in the number of gynecomastia surgeries has resulted in an increased need for anesthetic techniques with improved pain reduction, safety, and fewer complications. The aim of this work is to compare the efficacy of ultrasound guided thoracic interfascial plane block and ultrasound guided thoracic paravertebral block for …

anesthesia
local anesthetics
gynecomastia
local anesthesia
  • 0 views
  • 05 Aug, 2020
PB2452 in Ticagrelor-treated Patients With Uncontrolled Major or Life-Threatening Bleeding or Requiring Urgent Surgery or Invasive Procedure

This is a multi-center, open-label, prospective single-arm study of reversal of the antiplatelet effects of ticagrelor with PB2452 in patients who present with uncontrolled major or life-threatening bleeding or who require urgent surgery or invasive procedure. Approximately 200 patients will be enrolled at approximately 200 centers worldwide. Patients with reported …

stroke
heart surgery
packed red blood cells
postoperative hemorrhage
orthopedic surgery
  • 0 views
  • 16 Feb, 2024
  • 6 locations
Carrimycin in Patients With Locally Advanced Recurrent or Metastatic HNSCC (Non NPC): A Phase I Trial

The trial is a study conducted to evaluate the safety, tolerability and PK characteristics of Carrimycin tablet and measure its anti-tumor efficacy initially in the treatment of patients with locally advanced, recurrent, or metastatic head and neck squamous cell carcinoma (non NPC).

serum total bilirubin
metastatic head and neck squamous cell carcinoma
metastatic head and neck squamous cell cancer
aptt
carcinoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
Effect of Progesterone Therapy on Traumatic Subarachinoid Haemorrhage on Clinical Outcome and Resistive Vasculer Indices of Middle Cerebral Artery Transcranial Doppler

Traumatic subarachinoid hemorrhage is associated with serious complications related to mortality . Delayed neuronal ischemia and rebleeding are most common and serious. Progesterone can delay both .

traumatic brain injury
ischemia
progesterone therapy
progesterone
progestin therapy
  • 0 views
  • 16 Feb, 2024
  • 1 location
SLOW-Slower Progress of caLcificatiOn With Vitamin K2

A randomized 12-month trial will include two groups of 100 individuals aged over 50 years, with asymptomatic mild to moderate Aortic valve stenosis (AVA > 1 cm2, Vmax < 4 m/s). The first group of 100 individuals will serve as the intervention group that will receive 300 mcg of K2 …

stenosis
vitamin
chronic kidney disease
vitamin k antagonists
aortic stenosis
  • 0 views
  • 16 Feb, 2024
  • 2 locations
A Randomized Controlled Trial of AppS to Home Monitor Your Asthma

The objective of this study is to design, implement, and evaluate the impact of an adapted health information technology(IT)-enabled practice model for asthma symptom monitoring using patient-reported outcomes (PROs) in a primary care setting. Adults over 18 years of age with asthma will be recruited at four primary care clinics …

  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of MRG002 in Patients With HER2-Positive Advanced Solid Tumors and Locally Advanced or Metastatic Gastric/Gastroesophageal Junction (GEJ) Cancer

The objective of this study is to assess the safety, efficacy, and pharmacokinetics of MRG002, as well as the immunogenicity as defined by the incidence of anti-drug antibody (ADA) of MRG002 in patients with HER2-positive advanced solid tumors and locally advanced or metastatic gastric/gastroesophageal junction (GEJ) cancer.

  • 0 views
  • 16 Feb, 2024
  • 1 location
Mavrilimumab to Reduce Progression of Acute Respiratory Failure in COVID-19 Pneumonia and Systemic Hyper-inflammation

The purpose of this prospective, Phase 2, multicenter, blinded, randomized placebo controlled study is to demonstrate that early treatment with mavrilimumab prevents progression of respiratory failure in patients with severe COVID-19 pneumonia and clinical and biological features of hyper-inflammation.

SARS
x-rays
hypoxia
fever
acute respiratory syndrome (sars)
  • 0 views
  • 01 Feb, 2023
  • 2 locations
The SMART A Exercise Study :''The SMART Study'' (SMART)

Despite the promising data emanating from trials investigating the effectiveness of advanced hybrid closed loop (AHCL) insulin delivery systems in managing glycaemia in those with type 1 diabetes (T1D), we currently know little about their efficacy in optimising glycaemia when physical activity is factored into the equation. With the introduction …

  • 0 views
  • 26 Nov, 2021
  • 1 location