Found 1007 clinical trials
Effect of Academic Detailing to Reduce Opioid Prescribing in Dentistry
This will be achieved through educating dentists about best practices for opioid prescribing and includes three continuing education (CE) credits and one (or two) academic detailing (AD) visits. The cohort of 90 dentists who are enrolled to the CE will be randomized into two groups upon enrollment.
- 0 views
- 16 Feb, 2024
- 1 location
No Opioids PrescrIptions On Discharge After Surgery
Opioid analgesics are routinely prescribed for these patients for post-operative pain control. Even a short exposure to opioids in opioid-nave patients following minor or major surgery has been associated with de novo habitual or persistent use of opioids in 5-30% of patients.
- 0 views
- 16 Feb, 2024
- 1 location
INDV-2000 First in Human
This study will be a single ascending dose (SAD) study conducted to identify the maximum tolerated dose (MTD). After completion of the SAD portion of the study and acceptable safety evaluation, a food-interaction, single-dose study under fed and fasted conditions will be conducted.
- 0 views
- 16 Feb, 2024
- 1 location
Managing Pain and Symptom Burden Caused by Chemotherapy in People With Myeloma or Lymphoma
The purpose of this study is to find out whether acupuncture treatments can reduce the need for opioid medication when managing pain caused by chemotherapy. The study will compare the effects of adding acupuncture to usual pain management with those of usual pain management alone, in reducing opioid use by …
- 0 views
- 16 Feb, 2024
- 2 locations
The Effect of Chronic Pain on Delay Discounting in Methadone Patients
The epidemic of opioid overdose deaths continues to rise, killing more persons in 2017 than HIV/AIDS at the height of that epidemic. Medication assisted treatment, including methadone and buprenorphine, is the standard of care for the treatment of opioid use disorder (OUD).
- 0 views
- 16 Feb, 2024
- 1 location
Optimization of NIBS for Treatment of Addiction
The purpose of this study is to assess the effects of transcranial Direct Current Stimulation (tDCS) applied in conjunction with Transcranial Ultrasound (TUS) for the treatment of addiction in opiate use disorder with chronic pain. The investigators hypothesize that there will be a decrease in drug use and improved psychosocial …
- 0 views
- 16 Feb, 2024
- 1 location
Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic Meniscus Surgery
However, these agents are associated with several side effects, including nausea/vomiting, constipation, and somnolence. In addition, opioid agents have a significant potential for abuse in comparison to non-narcotic analgesics. In light of the rising opioid epidemic and nationwide initiatives to limit narcotic usage, surgeons must explore alternate pain modalities in …
- 0 views
- 16 Feb, 2024
- 1 location
The Rhode Island Prescription and Illicit Drug Study
This study will test the efficacy of a novel drug-checking intervention to prevent fatal and non-fatal overdose among people who use drugs (PWUD), who are 18-65 years old at the time of enrollment. The investigators will evaluate whether the incorporation of rapid fentanyl testing into a theory-driven overdose education and …
- 0 views
- 16 Feb, 2024
- 1 location
Ketamine Analgesia in Third Molar Surgery
When the patients go home on the same day, this demands safe pain relief. A reduction of morphine (opioid) use is sought because of side effects and the dependency risk. An effective alternative to opioids is ketamine, which lacks the side effects of opioids but provides powerful analgesic effects.
- 0 views
- 16 Feb, 2024
- 1 location
Superficial Cervical Plexus Block for Orthognathic Surgery
US-guided superficial cervical plexus block (SCPB) may be used for several head and neck surgeries. Local anesthetic is injected under the sternocleidomastoid muscle for SCPB. It has lower complication rate compared to the deep cervical plexus block. Postoperative pain management is important in patients underwent orthognathic surgery. Effective pain treatment …
- 0 views
- 05 Aug, 2020