Found 144 clinical trials
Immune Response and Risk of Serious Infection to SARS-Cov2
One hypothesis is that it is related to an inappropriate inflammatory response rather than a direct cytopathic effect of the virus. The objective of this study is to measure the intensity of the T lymphocyte response in patients hospitalized for Cov2 SARS infection in order to determine whether the intensity …
- 0 views
- 16 Feb, 2024
- 1 location
Viral Excretion in Contact Subjects at High/Moderate Risk of Coronavirus 2019-nCoV Infection. COVID-19.
In all cases, it is most often recommended that contact persons monitor their state of health and communicate it to the persons dedicated to this action. Whether such subjects become spreaders of the virus is not known, nor is the proportion of viral spreader who will develop a symptomatic infection.
- 0 views
- 16 Feb, 2024
- 17 locations
Non Inferiority Trial for Detection of nCOVID-19 Through Analysis of Exhaled Breath Aerosols
These are single use disposable breath capture devices with removable filters and fitted PVA strip that directly sample exhaled breath aerosols and therefore, directly sample the primary transmission route for the virus. They can be used independently and shipped for analysis for the presence of nCOVID-19 using established existing assays …
- 0 views
- 16 Feb, 2024
- 1 location
HFNC and NIV for COVID-19 Complicated by Respiratory Failure
High flow nasal cannula (HFNC) oxygen therapy and noninvasive ventilation (NIV) may offer respiratory support to patients with COVID-19 complicated by acute hypoxemic respiratory failure if conventional oxygen therapy (COT) fails to maintain satisfactory oxygenation but whether these respiratory therapies would lead to airborne viral transmission is unknown. Aims: This …
- 0 views
- 16 Feb, 2024
- 1 location
Prospective Natural History Study of Smoking Immune Cell Profiles Epigenetics and COVID-19
Objective To better understand how COVID-19 affects smokers and non-smokers immune systems before and after being infected with the virus. Eligibility Healthy people ages 30-55 who are a smokers or non-smokers who may potentially contract COVID-19 Design Participants will be screened over the phone.
- 0 views
- 05 Aug, 2020
COVID-19 Associated Lymphopenia Pathogenesis Study in Blood (CALYPSO)
With fewer lymphocytes, the body cannot effectively fight back against SARS CoV-2, the virus that causes COVID-19. Researchers want to better understand how SARS-CoV-2 affects these blood cells. This information may give them ideas for new treatments.
- 0 views
- 16 Feb, 2024
- 3 locations
Patient Outcome of Cardiac Surgery During the COVID-19 Pandemic
This study will describe the recovery process of patients undergoing cardiac surgery during the covid-19 pandemic. This will focus on hemodynamic failure and organ dysfunction after surgery. Capturing real-world data and sharing international experience will inform the management of this complex group of patients who undergo surgery throughout the COVID-19 …
- 0 views
- 16 Feb, 2024
- 1 location
Repeated Employee Testing for Understanding Our Recovery to Normal
The purpose of this research study is 1) to conduct a prospective longitudinal surveillance research trial, enrolling up to 200 CCHMC employees as they come back to work, and then following their clinical and laboratory parameters for up to 12 months; and 2) to support the ongoing development of diagnostic …
- 0 views
- 16 Feb, 2024
- 1 location
A Study to Assess the Feasibility of Screening for SARS-CoV-2 Among Healthy Workers
This is a prospective, epidemiological, cohort study to assess the feasibility of screening healthy asymptomatic workers for the presence of severe acute respiratory syndrome SARS-CoV-2 by pharyngeal swaps and serology at baseline, day 21 and day 40.
- 0 views
- 16 Feb, 2024
- 1 location
Neuro-COVID-19: Neurological Complications of COVID-19
The prevalence and typical patterns of neurological complications in hospitalized COVID-19 patients admitted to the intensive care units of the University Hospital Zurich will be investigated. The impact of neurological complications among COVID-19 patients on mortality, functional outcome, and organizational outcomes will be analyzed.
- 0 views
- 05 Aug, 2020