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Found 216 clinical trials
Feasibility and Effectiveness of Delivering Cognitive Behaviour Therapy Through Online Psychotherapy Tool (OPTT) for Depression

This study also aims to determine the difference in efficacy between e-CBT alone, pharmacotherapy alone and e-CBT with pharmacotherapy as it relates to various demographic characteristics (i.e., gender, age, socioeconomic status, etc.).

psychiatric disorder
depression
psychotherapy
anxiety
depressive disorder
  • 0 views
  • 16 Feb, 2024
  • 1 location
Toripalimab Plus Concurrent Chemo-radiotherapy for Unresectable Locally Recurrent Nasopharyngeal Carcinoma

Through multicenter, open-label, randomised clinical trials, we intend to demonstrate that concurrent and adjuvant PD-1 treatment added to concurrent chemo-radiotherapy could further decrease the rate of disease progression and improve the survival outcome of patients with unresectable locally recurrent nasopharyngeal carcinoma compared with those treated with concurrent chemo-radiotherapy alone.

adjuvant
karnofsky performance status
creatinine clearance rate
nasopharyngeal carcinoma
toripalimab
  • 0 views
  • 05 Aug, 2020
Adjuvant Chemotherapy for Triple Negative Breast Cancer Patients With Residual Disease After Neoadjuvant Chemotherapy

This study will evaluate the efficacy and safety of antharcycline-based adjuvant chemotherapy compared with observation in triple negative breast cancer (TNBC) patients with residual invasive disease after platinum and taxanes based neoadjuvant chemotherapy.

triple negative breast cancer
breast surgery
HER2
adjuvant
tumor excision
  • 0 views
  • 16 Feb, 2024
  • 1 location
Radical Radiotherapy and Chemotherapy Combined With Maintenance Chemotherapy in the Treatment of Stage N3 NPC

This study is a randomized, phase II, prospective, multicenter clinical trial to evaluate the efficacy and safety of radical chemoradiotherapy plus oral capecitabine/teggio for 1 year in patients with N3.

nasopharyngeal carcinoma
alt/ast
carcinoma
chemoradiotherapy
capecitabine
  • 0 views
  • 16 Feb, 2024
  • 1 location
Improving Survivorship Care for Older Adults After Chemotherapy

The researchers want to find out if older adults receiving a survivorship care plan followed by a geriatric assessment visit improves quality of life and satisfaction with care compared to receiving only a survivorship care plan for older adults who have completed chemotherapy for cancer treatment.

  • 0 views
  • 05 Aug, 2020
Platinum-Based Chemotherapy and Durvalumab for the Treatment of Stage IIIB or IV Non-small Cell Lung Cancer

The purpose of this study is to find out if the combination of chemotherapy in combination with the immune therapy drug durvalumab would be efficacious and have an acceptable toxicity profile in patients with advanced non-small cell lung cancer.

colitis
in situ carcinoma
neuropathy
pulmonary disease
nervous system
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharyngeal Cancer.

The objective of this trial is to study the efficacy of treatment of human papilloma virus (HPV) related oropharyngeal cancer with chemotherapy followed by Transoral Robotic Surgery (TORS) as definitive treatment. Current treatment of oropharyngeal cancer are chemo-radiotherapy.

karnofsky performance status
papilloma
docetaxel
carcinoma
squamous cell carcinoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
The Efficacy of Adjuvant Chemotherapy in Locally Advanced Cervical Cancer

The aim of this trial was to evaluate the efficacy of adjuvant chemotherapy in the locally advanced cervical cancer with residual lesions after concurrent chemoradiation therapy.

cervical cancer stage
concurrent chemoradiation
cisplatin
cervical cancer
cancer
  • 0 views
  • 05 Aug, 2020
De-escalated Conformal Radiation Expedited Sequentially With Chemotherapy for Endometrial Cancer

The goal of this study is to evaluate short course radiation in the post-operative female pelvis after hysterectomy in stage III-IVA endometrial adenocarcinoma patients, or any stage patients with uterine serous or carcinosarcoma histology. The investigators hypothesize that short course pelvic radiation will have an acute and late grade 3-4 …

pelvic radiation
cancer
neutrophil count
endometrial adenocarcinoma
carcinosarcoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
Anti-HER2 Bispecific Antibody ZW25 Activity in Combination With Chemotherapy With/Without Tislelizumab

The purpose of the study is to assess the safety, tolerability and preliminary antitumor activity of ZW25 in combination with docetaxel in participants with human epidermal growth factor receptor 2 (HER2)-positive breast cancer, and ZW25 in combination with tislelizumab and chemotherapy in participants with HER2-positive gastric/gastroesophageal Junction (GEJ) adenocarcinoma

drug evaluation
capecitabine
glomerular filtration rate
docetaxel
gastric adenocarcinoma
  • 0 views
  • 16 Feb, 2024
  • 12 locations