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Found 796 clinical trials
Study of NK Combined With Chemotherapy for Advanced Solid Tumor

Combinations Natural Killer Cell (NK) With chemotherapy treatment may enhance the immune response and stop cancer cells from growing.

brain metastases
psychiatric disorder
advanced solid tumor
metastasis
advanced malignant solid tumor
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of CS3007 in Subjects With Gastrointestinal Stromal Tumor

This study is an open-label, multicenter, phase I/II study to evaluate the safety, PK and clinical efficacy of avapritinib in Chinese subjects with unresectable or metastatic GIST. The study consists of two parts: dose escalation (phase I) and dose expansion (phase II).

kinase inhibitor
pdgfra gene
gastrointestinal stromal tumor
stromal tumor
imatinib
  • 0 views
  • 16 Feb, 2024
  • 1 location
DS-6157a in Participants With Advanced Gastrointestinal Stromal Tumor (GIST)

This study will assess the safety, efficacy, and pharmacokinetics of DS-6157a in participants with advanced gastrointestinal stromal tumors (GIST).

pdgfra d842v mutation
major surgery
metastasis
liver metastasis
platelet count
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Imaging of Tumour Microenvironment in Patients With Oropharyngeal Head and Neck Squamous Cell Carcinoma Using RGD PET/CT Imaging

However, the incidence of human papillomavirus (HPV) related oropharyngeal carcinomas is increasing. It is known that HPV+ and HPV- tumors have a different reaction to (chemo)radiotherapy. The exact mechanisms underlying these differences is not yet known but might be caused by changes in vascularity.

human papillomavirus
carcinoma
oropharyngeal carcinoma
ct perfusion
squamous cell carcinoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of HMPL-306 in Patients With IDH1 and/or IDH2 Mutation of Relapsed/Refractory Myeloid Leukemia/Neoplasms

Phase I, multicenter study to evaluate the safety, pharmacokinetics, pharmacodynamics and efficacy of HMPL-306 in Patients of Relapsed/Refractory Myeloid Leukemia/Neoplasms with IDH1 and/or IDH2 Mutation.

refractory acute myeloid leukemia (aml)
chronic myelomonocytic leukemia
idh2 gene mutation
IDH2
leukemia
  • 0 views
  • 16 Feb, 2024
  • 1 location
Optimising Radiation Therapy in Head and Neck Cancers Using Functional Image-Guided Radiotherapy and Novel Biomarkers

This is a non-randomised study to develop personalised treatment approaches in participants with Locally Advanced Head and Neck Cancer (HNC) of the oropharynx and base of skull by integrating the use of MR-guided Adaptive Radiotherapy (MRgRT) and functional image-guided radiotherapy (FIgRT).

chemo-radiotherapy
carcinoma
neck cancer
platinum-based chemotherapy
head and neck carcinoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
4SCAR-CD44v6 T Cell Therapy Targeting Cancer

The purpose of this clinical trial is to assess the feasibility, safety and efficacy of 4SCAR-CD44v6 T-cell therapy targeting multiple cancers. The study also aims to learn more about the function of the CD44v6 CAR-T cells and their persistency in the patients.

  • 0 views
  • 05 Aug, 2020
Radiofrequency Ablation (RFA) in Breast Tumors

To validate the efficacy and safety of the cool-tip ablation method for breast tumors smaller than 2 cm.

invasive ductal breast carcinoma
breast tumor
radiofrequency ablation
ductal carcinoma
  • 0 views
  • 05 Aug, 2020
Study of DC-CIK Combined With Chemotherapy for Advanced Solid Tumor

Combinations of Dendritic cell-activated cytokine-induced killer cell (DC-CIK) With chemotherapy treatment may enhance the immune response and stop cancer cells from growing.

brain metastases
psychiatric disorder
advanced solid tumor
metastasis
advanced malignant solid tumor
  • 0 views
  • 16 Feb, 2024
  • 1 location
Study of Bcl-2 Inhibitor BGB-11417 in Participants With Mature B-Cell Malignancies

The purpose of this study is to determine the safety, tolerability; Recommended Phase 2 Dose (RP2D), optimal ramp-up dosing schedule; and to evaluate preliminary activity of BGB-11417 monotherapy.

  • 0 views
  • 16 Feb, 2024
  • 2 locations