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Found 237 clinical trials
Hyperpolarized Imaging for New Treatments

The introduction of triple combination CFTR modulator therapy for patients with Cystic Fibrosis (CF) with at least one copy of the deltaF508 mutation is expected to provide major health benefits, but will also require novel outcome measures that can detect CF lung disease at an early stage, capture the efficacy …

antibiotic therapy
cystic fibrosis
multiple breath washout
pulmonary disease
sweat test
  • 0 views
  • 16 Feb, 2024
  • 4 locations
Safety and Effectiveness Assessment of the MakAir Artificial Ventilator

The objective of our study is to carry out an evaluation of the safety and the effectiveness of the use of the MakAir respirator as useful supplement in situation of shortage of technical devices of assistance to the mechanical invasive ventilation, related to COVID-19 through a protocol in 3 successive …

fraction of inspired oxygen (fio2)
respiratory distress
mechanical ventilation
pao2
acute respiratory distress
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Study of Hypofractionated Radiotherapy Alone in Locally Advanced Nonsmall Cell Lung Cancer Patients

The purpose of this research study is to find out what effects (good or bad) may come from a new way of doing radiation therapy for lung cancer. This study is for patients who are not able to get surgery or chemotherapy with their radiation. The way of doing radiation …

hypofractionated radiation therapy
non-small cell lung cancer
nonsmall cell lung cancer stage
small cell lung cancer
stage ii non-small cell lung cancer
  • 0 views
  • 05 Aug, 2020
Evaluation of the Right Ventricular Systolic Function Using Real-time Three-dimensional Echocardiography in Intensive Care Unit Patients

Right ventricular failure (RVF) is an independent factor of mortality for many pulmonary diseases. Currently, RVF is defined as the incapacity of the RV to maintain the flow without dilating to use the Frank-Starling law (i.e., increase of the ejection volume associated to an increase of the preload).

respiratory distress
3d echocardiography
pulmonary disease
tapse
infarction
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Study to Assess Efficacy and Safety Relative to Standard of Care in Patients With COVID-19 Pneumonia

To assess the clinical efficacy of ANG-3777 relative to the standard of care in reducing the severity and progression of pulmonary and renal dysfunction and mortality in adult patients hospitalized with COVID-19 pneumonia

SARS
renal impairment
chest imaging
pneumonia
acute respiratory syndrome (sars)
  • 0 views
  • 05 Aug, 2020
Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal Cancer

Participating in the program may improve knowledge and confidence about follow-up care, communication with cancer care and primary care doctors, and quality of life after cancer treatment in non-small cell lung cancer or colorectal cancer survivors.

stage ia3 lung cancer ajcc v8
cancer care
stage iib lung cancer ajcc v8
small cell lung cancer
non-small cell lung cancer
  • 4 views
  • 16 Feb, 2024
  • 1 location
Implementation of an Early Rehabilitation Program for the Patient With Lung Transplantation: From the ICU to Home.

It is also expected that the patients in the experimental group will soon be able to normalize their oxygen consumption a year after lung transplantation.

cardiopulmonary exercise testing
treatment protocols
spirometry
rehabilitation therapy
double lung transplantation
  • 0 views
  • 16 Feb, 2024
  • 1 location
Platinum-Based Chemotherapy and Durvalumab for the Treatment of Stage IIIB or IV Non-small Cell Lung Cancer

The purpose of this study is to find out if the combination of chemotherapy in combination with the immune therapy drug durvalumab would be efficacious and have an acceptable toxicity profile in patients with advanced non-small cell lung cancer.

hyperbilirubinemia
pd-l1
measurable disease
celiac disease
solid tumors
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Best Supportive Care With or Without Low Dose Whole Lung Radiation Therapy for the Treatment of COVID-19

This phase III trial compares low dose whole lung radiation therapy to best supportive care plus physicians choice in treating patients with COVID-19 infection. Low dose whole lung radiation therapy may work better than the current best supportive care and physician's choice in improving patients' clinical status, the radiographic appearance …

cough
chest imaging
pneumonia
acute respiratory syndrome (sars)
blood tests
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study to Evaluate Efficacy and Safety of PTC299 in Hospitalized Participants With Coronavirus (COVID-19)

This is a randomized, double-blind, placebo-controlled, multicenter, 28-day study of adult participants hospitalized with COVID-19, with a safety follow-up telephone call at Day 60.

SARS
cough
oximetry
chest x-ray
x-rays
  • 0 views
  • 16 Feb, 2024
  • 5 locations