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Found 4313 clinical trials
Program-P1  

Test Program-01

  • 0 views
  • 17 Nov, 2025
Capivasertib+Abiraterone as Treatment for Patients With Metastatic Hormone-sensitive Prostate Cancer and PTEN Deficiency

This study will assess the efficacy and safety of capivasertib plus abiraterone (+prednisone/prednisolone) plus androgen deprivation therapy (ADT) versus placebo plus abiraterone (+prednisone/prednisolone) plus ADT in participants with mHSPC whose tumours are characterised by PTEN deficiency. The intention of the study is to demonstrate that in participants with mHSPC, the …

metastasis
steroid therapy
prednisolone
bone metastases
bone lesion
  • 0 views
  • 16 Feb, 2024
  • 107 locations
A Phase 1/2 Study of SHP648 an Adeno-Associated Viral Vector for Gene Transfer in Hemophilia B Subjects

The purpose of this study is to evaluate the safety and dose escalation of SHP648 an adeno-associated viral vector for gene transfer in hemophilia B participants.

viral vector
christmas disease
hemophilia
prophylactic
gene therapy
  • 0 views
  • 16 Feb, 2024
  • 17 locations
Efficacy and Safety of the Combination of Rucaparib (PARP Inhibitor) and Atezolizumab (Anti-PD-L1 Antibody) in Patients With DNA Repair-deficient or Platinum-sensitive Solid Tumors

The primary objective of the trial is to evaluate the antitumor activity of atezolizumab and rucaparib in patients with selected advanced solid tumors as measured by the Overall Response Rate

metastasis
parp inhibitor
rucaparib
gilbert's syndrome
warfarin
  • 0 views
  • 16 Feb, 2024
  • 1 location
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