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Found 15 clinical trials
Continuous Versus Cyclical OCP Use in PCOS (CCOUP)

The mainstay treatment for females with Polycystic Ovary Syndrome (PCOS) has long been a combination of an oral contraceptive pill or OCP (containing both estrogen and progestin) along with an anti-androgen medication (such as Spironolactone) to not only prevent chronic anovulation but also suppress elevated testosterone levels and its clinical …

Accepts healthy volunteers
  • 0 views
  • 04 Apr, 2022
  • 2 locations
Naproxen Pharmacogenetic Study (Project 1 Aim 2)

This is a mechanism-based study in healthy adults to determine the effect of the CYP2C9 M1L gene polymorphism on the functional activity of the encoded CYP2C9 enzyme towards the probe substrate naproxen. CYP2C9 activity will be evaluated by measurement of O-desmethyl naproxen and unchanged naproxen in 24-hour urine following administration …

  • 0 views
  • 16 Feb, 2024
  • 1 location
Effects of Fish Oil and Resistance Training on Muscle Mass and Function

Following 6 weeks of FO or PLA supplementation, subjects will repeat all initial biometric, strength and neuromuscular testing, as well as a second, post-intervention blood draw.

resistance training
coconut oil
fatty acids
blood draw
omega-3 fatty acid
  • 0 views
  • 16 Feb, 2024
  • 1 location
Changes in Cellular Immune Profile During COVID-19 Infection

Clinical specimens are collected from individuals either recovered from or with active SARS-CoV-2 infection to support process and analytical development for a potential cell-based immunotherapy in preclinical research, SRPH-CVD-01. SRPH-CVD-01 is an allogeneic cell-based immunotherapy candidate to be investigated in a subsequent clinical trial under a future FDA IND to …

leukapheresis
SARS
infection clinical
acute respiratory syndrome (sars)
gene therapy
  • 0 views
  • 01 Feb, 2023
  • 1 location
Lutetium-177-PSMA-I&T in Oligo-metastatic Hormone Sensitive Prostate Cancer

  Radioligand therapy (RLT) using Lutetium-177 labelled PSMA is a promising new therapeutic approach to treat metastatic prostate cancer. This tumor-specific treatment is directed against prostate-specific membrane antigen (PSMA), which is overexpressed in prostate cancer cells. In the last few years, several lutetium-177 (177Lu, emitter) labeled PSMA ligands have been …

adenocarcinoma of prostate
immunological adjuvant
testosterone
metastasis
pet/ct scan
  • 4 views
  • 22 Aug, 2020
Long-term Consumption of Resistant Starch Type-4 (RS4)

The primary objective of the current proposal is to determine the effectiveness of long-term consumption of Fibersym RW for improving blood lipids (including cholesterol) and body composition. The overall goal of this clinical research is to determine the potential effects that RS4 consumption may have on the prevention of obesity …

cholesterol measurement
blood lipids
LDL Cholesterol
  • 0 views
  • 16 Feb, 2024
  • 1 location
Serological Surveillance for COVID-19 in Central North Carolina

For this, a nasal or throat swab will be done, or saliva will be collected. They may do this test at the same visit as the blood draw, or they may schedule an extra visit. Around the time of their study visits, participants will take an online survey about themselves, …

acute respiratory syndrome (sars)
throat
covid-19
SARS
  • 0 views
  • 16 Feb, 2024
  • 1 location
COVID-19 in Baselland: Investigation and Validation of Serological Diagnostic Assays and Epidemiological Study of Sars-CoV-2 Specific Antibody Responses

The study is to investigate the antibody response in the blood and saliva of people with a known COVID-19 infection in the canton of Baselland.

antibody test
acute respiratory syndrome (sars)
covid-19
SARS
  • 0 views
  • 16 Feb, 2024
  • 1 location
Antigen Presentation and Lymphocyte Response in Parkinson's Disease  

The study involves a one time visit involving brief questionnaires and a blood draw of 30 mL (approximately 2 tablespoons) to be collected.

bradykinesia
tremor
muscle rigidity
resting tremor
  • 1784 views
  • 16 Feb, 2024
  • 3 locations
Early Onset Alzheimer's Disease Genomic Study  

The purpose of this study is to collect samples from patients with Early-Onset Alzheimer's disease (AD) and their immediate family members for molecular analysis. Samples will be studied in order to understand how molecular changes in the body are related to the development of the disease. Researchers will study your …

severe dementia
genetic testing
alzheimer's disease
dementia
  • 0 views
  • 16 Feb, 2024
  • 1 location