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Found 14 clinical trials
SAR408701 Versus Docetaxel in Previously Treated Carcinoembryonic Antigen-related Cell Adhesion Molecule 5 (CEACAM5) Positive Metastatic Non-squamous Non-small Cell Lung Cancer Patients

Primary Objectives: Study is designed with two primary endpoints that will be analyzed on randomized participants at the time of the cutoff date for each given analysis (progressive free survival [PFS] and overall survival [OS]). Study success is defined either on PFS or OS The primary objective is to determine …

pulmonary metastasis
platinum-based chemotherapy
immune checkpoint inhibitor
metastasis
squamous nsclc (non-small cell lung cancer)
  • 0 views
  • 04 Dec, 2020
  • 169 locations
SAR408701 Versus Docetaxel in Previously Treated Carcinoembryonic Antigen-related Cell Adhesion Molecule 5 (CEACAM5) Positive Metastatic Non-squamous Non-small Cell Lung Cancer Patients  

Primary Objectives: Study is designed with two primary endpoints that will be analyzed on randomized participants at the time of the cutoff date for each given analysis (progressive free survival [PFS] and overall survival [OS]). Study success is defined either on PFS or OS The primary objective is to determine …

pulmonary metastasis
platinum-based chemotherapy
immune checkpoint inhibitor
metastasis
squamous nsclc (non-small cell lung cancer)
  • 0 views
  • 21 Dec, 2020
  • 52 locations
MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment

In spinal cord tumors requiring surgical intervention, the resection difficulty is determined by two significant factors: tumor stiffness and adhesion to surrounding tissue. The stiffness of the tumor dictates the complexity of removal, while strong adhesion presents additional challenges during the surgical procedure.

Accepts healthy volunteers
  • 0 views
  • 25 Jul, 2023
  • 22 locations
Reconstruction of Atrophic Maxillary Ridges Using Mandibular Blocks With and Without Coverage Using Collagen Membrane

Is the use of collagen membrane on top of particulate bone mixture covered by onlay bone block in Maxilla better than the use of mixture of particulate bone covered by onlay bone block without the use of collagen membrane, in terms of bone quality and bone quantity?

  • 0 views
  • 05 Aug, 2020
Multi-4SCAR-T Therapy Targeting Breast Cancer

The purpose of this study is to assess the feasibility, safety and efficacy of multiple 4th generation CAR-T cells targeting Her2, GD2, and CD44v6 surface antigen in breast cancer. Another goal of the study is to learn more about the activities of the multi-CAR T cells and their persistency in …

immunosuppressive agents
neutrophil count
serum bilirubin
immunosuppression
  • 2 views
  • 05 Aug, 2020
Prospective Clinical Trial of Onlay-carrying Patients

A record of the type of onlay will be made with respect to its extension, tooth or teeth to be treated, the material of clothing and the substrate on which the adhesion and cementing method, as well as the type of antagonist. To complete it, a complete clinical oral examination …

  • 0 views
  • 05 Aug, 2020
The Use of plasmaJet During Operative Laparoscopy for Endometriosis

Therefore, the use of ultrasound, laser or plasma energy can potentially reduce damage to surrounding tissues and prevent adhesion formation. In addition, ablation of the internal surface of endometriomas can be an effective alternative to cystectomy. The PlasmaJet system uses argon plasma which is released as kinetic, light and / …

adhesion
laparoscopy
endometriosis
endometrioma
  • 0 views
  • 16 Feb, 2024
  • 1 location
Internal Limiting Membrane Peeling in Proliferative Diabetic Retinopathy

Subject/Participant Groups: Study Group: Subjects undergo internal limiting membrane (ILM) peeling during vitrectomy for the indication of tractional retinal detachment Control Group: Subjects do not undergo ILM peeling during vitrectomy for the indication of tractional retinal detachment

diabetic retinopathy
vitrectomy
retinal detachment
proliferative diabetic retinopathy
retinopathy
  • 0 views
  • 16 Feb, 2024
  • 1 location
Effect of Nutritional Supplementation and Pulmonary Rehabilitation on the Clinical Status of HF and COPD

Cardiovascular diseases (CVD) are the leading cause of death in the world and our country. The prevalence of Heart Failure (HF) is 1-2% in the adult population in developed countries, up to 10% among people 70 years of age. Concerning COPD, it is estimated that by 2030 will be the …

pulmonary rehabilitation
lung disease
lung disorder
pulmonary function test
cardiovascular disease
  • 0 views
  • 16 Feb, 2024
  • 1 location
Biomarkers in Polyradiculoneuropathies

The investigators found that antibodies target cell adhesion molecules at nodes of Ranvier in 10% of patients with chronic inflammatory demyelinating neuropathy (CIDP), another disabling neuromuscular disease affecting peripheral nerves.

neuromuscular diseases
cell adhesion molecules
ion channels
neuropathy
fibres
  • 0 views
  • 16 Feb, 2024
  • 1 location